Total body water (TBW) obtained by deuterium dilution (TBWD) in 45 adult Indian males of low body mass index was compared with values obtained from bioelectrical impedance (TBWImp) and two anthropometry-based prediction equations. Bioelectrical impedance significantly underestimated TBW when compared with deuterium dilution, by 2.75 SD 2.86 kg. Comparisons of the anthropometry-based prediction equations demonstrated that TBW was overestimated by 0.87 SD 2.49 kg, and 2.47 SD 2.57 kg, respectively. Since all parameters in the bioelectrical impedance method were standardized, the difference in the values could have been because of the equation used. Therefore, a fresh equation for the measurement of TBW by the bioelectrical impedance method was derived using the variables of height2/impedance and weight. New prediction equations for TBW were also derived based on anthropometric variables of weight and height. Body weight has the greatest influence in the prediction equations for TBW, and the equation derived was TBW (kg) = 0.533 x body weight (kg) + 3.77, SEE = 2.4 kg. Using height2/impedance gave the relationship: TBW (kg) = 0.568 body weight-0.04 height2/impedance + 4.35, SEE = 1.9 kg.