Effectiveness of atorvastatin for reducing low-density lipoprotein cholesterol to National Cholesterol Education Program treatment goals

M H Davidson; J W Nawrocki; S R Weiss; S L Schwartz; P J Lupien; P H Jones; H E Haber; D M Black

doi:10.1016/s0002-9149(97)00360-3

Effectiveness of atorvastatin for reducing low-density lipoprotein cholesterol to National Cholesterol Education Program treatment goals

Am J Cardiol. 1997 Aug 1;80(3):347-8. doi: 10.1016/s0002-9149(97)00360-3.

Authors

M H Davidson¹, J W Nawrocki, S R Weiss, S L Schwartz, P J Lupien, P H Jones, H E Haber, D M Black

Affiliation

¹ Chicago Center for Clinical Research, Illinois 60610, USA.

PMID: 9264433
DOI: 10.1016/s0002-9149(97)00360-3

Abstract

Atorvastatin is a highly efficacious hydroxymethylglutaryl-coenzyme A reductase inhibitor that has been shown to reduce low-density lipoprotein cholesterol by 40% to 60%. Monotherapy with atorvastatin (10 to 80 mg/day) is well-tolerated, convenient, and appears to be effective for achieving National Cholesterol Education Program treatment goals in most patients, regardless of risk status.

Publication types

Clinical Trial
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Anticholesteremic Agents / administration & dosage
Anticholesteremic Agents / therapeutic use*
Atorvastatin
Cholesterol, LDL / blood*
Heptanoic Acids / administration & dosage
Heptanoic Acids / therapeutic use*
Humans
Male
Middle Aged
Pyrroles / administration & dosage
Pyrroles / therapeutic use*
Retrospective Studies
Treatment Outcome

Substances

Anticholesteremic Agents
Cholesterol, LDL
Heptanoic Acids
Pyrroles
Atorvastatin