Myocardial overexpression of adrenergic receptors and receptor kinases

Adv Pharmacol. 1998:42:502-6. doi: 10.1016/s1054-3589(08)60799-1.

Authors

W J Koch¹, R J Lefkowitz, C A Milano, S A Akhter, H A Rockman

Affiliation

¹ Department of Surgery, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710, USA.

PMID: 9327950
DOI: 10.1016/s1054-3589(08)60799-1

No abstract available

MeSH terms

Animals
Cattle
Cyclic AMP-Dependent Protein Kinases / biosynthesis
G-Protein-Coupled Receptor Kinase 5
GTP-Binding Proteins / metabolism
Heart / physiology*
Heart Rate
Humans
Mice
Mice, Transgenic
Myocardial Contraction
Myocardium / metabolism*
Myosin Heavy Chains / biosynthesis
Myosin Heavy Chains / genetics
Protein Serine-Threonine Kinases*
Receptor Protein-Tyrosine Kinases / biosynthesis
Receptors, Adrenergic, beta-2 / biosynthesis
Receptors, Adrenergic, beta-2 / genetics
Receptors, Adrenergic, beta-2 / physiology*
Recombinant Fusion Proteins / biosynthesis
Signal Transduction
Up-Regulation
beta-Adrenergic Receptor Kinases

Substances

Receptors, Adrenergic, beta-2
Recombinant Fusion Proteins
Receptor Protein-Tyrosine Kinases
Protein Serine-Threonine Kinases
Cyclic AMP-Dependent Protein Kinases
beta-Adrenergic Receptor Kinases
G-Protein-Coupled Receptor Kinase 5
GRK5 protein, human
Grk5 protein, mouse
GTP-Binding Proteins
Myosin Heavy Chains