Duff K - Search Results

1

Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.

Begley JG, Duan W, Chan S, Duff K, Mattson MP. Begley JG, et al. Among authors: duff k. J Neurochem. 1999 Mar;72(3):1030-9. doi: 10.1046/j.1471-4159.1999.0721030.x. J Neurochem. 1999. PMID: 10037474 Free article.

2

Modulation of A(beta) peptides by estrogen in mouse models.

Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Zheng H, et al. Among authors: duff k. J Neurochem. 2002 Jan;80(1):191-6. doi: 10.1046/j.0022-3042.2001.00690.x. J Neurochem. 2002. PMID: 11796757 Free article.

3

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.

Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y. Hirata-Fukae C, et al. Among authors: duff ke. Brain Res. 2008 Jun 24;1216:92-103. doi: 10.1016/j.brainres.2008.03.079. Epub 2008 Apr 10. Brain Res. 2008. PMID: 18486110

4

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K. Barrow PA, et al. Among authors: duff k. Neurobiol Dis. 2000 Apr;7(2):119-26. doi: 10.1006/nbdi.1999.0276. Neurobiol Dis. 2000. PMID: 10783295

5

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

Tsai J, Grutzendler J, Duff K, Gan WB. Tsai J, et al. Among authors: duff k. Nat Neurosci. 2004 Nov;7(11):1181-3. doi: 10.1038/nn1335. Epub 2004 Oct 10. Nat Neurosci. 2004. PMID: 15475950

6

Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain.

Wengenack TM, Whelan S, Curran GL, Duff KE, Poduslo JF. Wengenack TM, et al. Among authors: duff ke. Neuroscience. 2000;101(4):939-44. doi: 10.1016/s0306-4522(00)00388-2. Neuroscience. 2000. PMID: 11113343

7

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P. Andorfer C, et al. Among authors: duff k. J Neurochem. 2003 Aug;86(3):582-90. doi: 10.1046/j.1471-4159.2003.01879.x. J Neurochem. 2003. PMID: 12859672 Free article.

8

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479

9

Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease.

Barton AJ, Crook BW, Karran EH, Brown F, Dewar D, Mann DM, Pearson RC, Graham DI, Hardy J, Hutton M, Duff K, Goate AM, Clark RF, Roberts GW. Barton AJ, et al. Among authors: duff k. Neurodegeneration. 1996 Sep;5(3):213-8. doi: 10.1006/neur.1996.0029. Neurodegeneration. 1996. PMID: 8910899

10

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.

Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K. Holcomb L, et al. Among authors: duff k. Nat Med. 1998 Jan;4(1):97-100. doi: 10.1038/nm0198-097. Nat Med. 1998. PMID: 9427614

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