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A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity.
Osier MV, Pakstis AJ, Soodyall H, Comas D, Goldman D, Odunsi A, Okonofua F, Parnas J, Schulz LO, Bertranpetit J, Bonne-Tamir B, Lu RB, Kidd JR, Kidd KK. Osier MV, et al. Among authors: kidd kk, kidd jr. Am J Hum Genet. 2002 Jul;71(1):84-99. doi: 10.1086/341290. Epub 2002 Jun 5. Am J Hum Genet. 2002. PMID: 12050823 Free PMC article.
Considerable haplotype diversity within the 23kb encompassing the ADH7 gene.
Han Y, Oota H, Osier MV, Pakstis AJ, Speed WC, Odunsi A, Okonofua F, Kajuna SL, Karoma NJ, Kungulilo S, Grigorenko E, Zhukova OV, Bonne-Tamir B, Lu RB, Parnas J, Schulz LO, Kidd JR, Kidd KK. Han Y, et al. Among authors: kidd kk, kidd jr. Alcohol Clin Exp Res. 2005 Dec;29(12):2091-100. doi: 10.1097/01.alc.0000191769.92667.04. Alcohol Clin Exp Res. 2005. PMID: 16385178
Evidence of positive selection on a class I ADH locus.
Han Y, Gu S, Oota H, Osier MV, Pakstis AJ, Speed WC, Kidd JR, Kidd KK. Han Y, et al. Among authors: kidd kk, kidd jr. Am J Hum Genet. 2007 Mar;80(3):441-56. doi: 10.1086/512485. Epub 2007 Jan 30. Am J Hum Genet. 2007. PMID: 17273965 Free PMC article.
280 results