Fontana A - Search Results

1

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity.

Morelli AE, Larregina AT, Smith-Arica J, Dewey RA, Southgate TD, Ambar B, Fontana A, Castro MG, Lowenstein PR. Morelli AE, et al. Among authors: fontana a. J Gen Virol. 1999 Mar;80 ( Pt 3):571-583. doi: 10.1099/0022-1317-80-3-571. J Gen Virol. 1999. PMID: 10091995

2

Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand.

Ambar BB, Frei K, Malipiero U, Morelli AE, Castro MG, Lowenstein PR, Fontana A. Ambar BB, et al. Among authors: fontana a. Hum Gene Ther. 1999 Jul 1;10(10):1641-8. doi: 10.1089/10430349950017644. Hum Gene Ther. 1999. PMID: 10428209

3

FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

Larregina AT, Morelli AE, Dewey RA, Castro MG, Fontana A, Lowenstein PR. Larregina AT, et al. Among authors: fontana a. Gene Ther. 1998 Apr;5(4):563-8. doi: 10.1038/sj.gt.3300615. Gene Ther. 1998. PMID: 9614583

4

Ex vivo malignant glioma cells are sensitive to Fas (CD95/APO-1) ligand-mediated apoptosis.

Frei K, Ambar B, Adachi N, Yonekawa Y, Fontana A. Frei K, et al. Among authors: fontana a. J Neuroimmunol. 1998 Jul 1;87(1-2):105-13. doi: 10.1016/s0165-5728(98)00065-4. J Neuroimmunol. 1998. PMID: 9670851

5

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.

Hahne M, Rimoldi D, Schröter M, Romero P, Schreier M, French LE, Schneider P, Bornand T, Fontana A, Lienard D, Cerottini J, Tschopp J. Hahne M, et al. Among authors: fontana a. Science. 1996 Nov 22;274(5291):1363-6. doi: 10.1126/science.274.5291.1363. Science. 1996. PMID: 8910274

6

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity.

Schneider P, Holler N, Bodmer JL, Hahne M, Frei K, Fontana A, Tschopp J. Schneider P, et al. Among authors: fontana a. J Exp Med. 1998 Apr 20;187(8):1205-13. doi: 10.1084/jem.187.8.1205. J Exp Med. 1998. PMID: 9547332 Free PMC article.

7

Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo.

Rensing-Ehl A, Frei K, Flury R, Matiba B, Mariani SM, Weller M, Aebischer P, Krammer PH, Fontana A. Rensing-Ehl A, et al. Among authors: fontana a. Eur J Immunol. 1995 Aug;25(8):2253-8. doi: 10.1002/eji.1830250821. Eur J Immunol. 1995. PMID: 7545115

8

TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia.

Schlapbach R, Spanaus KS, Malipiero U, Lens S, Tasinato A, Tschopp J, Fontana A. Schlapbach R, et al. Among authors: fontana a. Eur J Immunol. 2000 Dec;30(12):3680-8. doi: 10.1002/1521-4141(200012)30:12<3680::AID-IMMU3680>3.0.CO;2-L. Eur J Immunol. 2000. PMID: 11169411 Free article.

9

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L).

Huang DC, Hahne M, Schroeter M, Frei K, Fontana A, Villunger A, Newton K, Tschopp J, Strasser A. Huang DC, et al. Among authors: fontana a. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14871-6. doi: 10.1073/pnas.96.26.14871. Proc Natl Acad Sci U S A. 1999. PMID: 10611305 Free PMC article.

10

Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas- and Fas ligand-deficient lpr and gld mice.

Malipiero U, Frei K, Spanaus KS, Agresti C, Lassmann H, Hahne M, Tschopp J, Eugster HP, Fontana A. Malipiero U, et al. Among authors: fontana a. Eur J Immunol. 1997 Dec;27(12):3151-60. doi: 10.1002/eji.1830271211. Eur J Immunol. 1997. PMID: 9464800

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