Southgate TD - Search Results

1

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity.

Morelli AE, Larregina AT, Smith-Arica J, Dewey RA, Southgate TD, Ambar B, Fontana A, Castro MG, Lowenstein PR. Morelli AE, et al. Among authors: southgate td. J Gen Virol. 1999 Mar;80 ( Pt 3):571-583. doi: 10.1099/0022-1317-80-3-571. J Gen Virol. 1999. PMID: 10091995

2

Molecular therapy in a model neuroendocrine disease: developing clinical gene therapy for pituitary tumours.

Castro MG, Southgate T, Lowenstein PR. Castro MG, et al. Trends Endocrinol Metab. 2001 Mar;12(2):58-64. doi: 10.1016/s1043-2760(00)00358-1. Trends Endocrinol Metab. 2001. PMID: 11167123 Review.

3

Gene transfer into enteric neurons of the rat small intestine in organ culture using a replication defective recombinant herpes simplex virus type 1 (HSV1) vector, but not recombinant adenovirus vectors.

Brown OA, Santer RM, Shering AF, Larregina AT, Morelli AE, Southgate TD, Castro MG, Lowenstein PR. Brown OA, et al. Among authors: southgate td. Gene Ther. 1997 Apr;4(4):331-8. doi: 10.1038/sj.gt.3300383. Gene Ther. 1997. PMID: 9176519

4

Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK.

Cowsill C, Southgate TD, Morrissey G, Dewey RA, Morelli AE, Maleniak TC, Forrest Z, Klatzmann D, Wilkinson GW, Löwenstein PR, Castro MG. Cowsill C, et al. Among authors: southgate td. Gene Ther. 2000 Apr;7(8):679-85. doi: 10.1038/sj.gt.3301147. Gene Ther. 2000. PMID: 10800091

5

Adenoviruses encoding HPRT correct biochemical abnormalities of HPRT-deficient cells and allow their survival in negative selection medium.

Southgate TD, Bain D, Fairbanks LD, Morelli AE, Larregina AT, Simmonds HA, Castro MG, Löwenstein PR. Southgate TD, et al. Metab Brain Dis. 1999 Dec;14(4):205-21. doi: 10.1023/a:1020728924026. Metab Brain Dis. 1999. PMID: 10850548

6

Gene transfer into neural cells in vitro using adenoviral vectors.

Southgate TD, Kingston PA, Castro MG. Southgate TD, et al. Curr Protoc Neurosci. 2001 May;Chapter 4:Unit 4.23. doi: 10.1002/0471142301.ns0423s13. Curr Protoc Neurosci. 2001. PMID: 18428483

7

Gene transfer into neural cells in vitro using adenoviral vectors.

Southgate T, Kroeger KM, Liu C, Lowenstein PR, Castro MG. Southgate T, et al. Curr Protoc Neurosci. 2008 Oct;Chapter 4:Unit 4.23. doi: 10.1002/0471142301.ns0423s45. Curr Protoc Neurosci. 2008. PMID: 18972378 Free PMC article.

8

Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.

Cartmell T, Southgate T, Rees GS, Castro MG, Lowenstein PR, Luheshi GN. Cartmell T, et al. J Neurosci. 1999 Feb 15;19(4):1517-23. doi: 10.1523/JNEUROSCI.19-04-01517.1999. J Neurosci. 1999. PMID: 9952427 Free PMC article.

9

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials.

Dewey RA, Morrissey G, Cowsill CM, Stone D, Bolognani F, Dodd NJ, Southgate TD, Klatzmann D, Lassmann H, Castro MG, Löwenstein PR. Dewey RA, et al. Among authors: southgate td. Nat Med. 1999 Nov;5(11):1256-63. doi: 10.1038/15207. Nat Med. 1999. PMID: 10545991

10

Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas.

Windeatt S, Southgate TD, Dewey RA, Bolognani F, Perone MJ, Larregina AT, Maleniak TC, Morris ID, Goya RG, Klatzmann D, Löwenstein PR, Castro MG. Windeatt S, et al. Among authors: southgate td. J Clin Endocrinol Metab. 2000 Mar;85(3):1296-305. doi: 10.1210/jcem.85.3.6482. J Clin Endocrinol Metab. 2000. PMID: 10720079

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