Schleyer E - Search Results

1

Leukaemic blasts differ from normal bone marrow mononuclear cells and CD34+ haemopoietic stem cells in their metabolism of cytosine arabinoside.

Braess J, Wegendt C, Feuring-Buske M, Riggert J, Kern W, Hiddemann W, Schleyer E. Braess J, et al. Among authors: schleyer e. Br J Haematol. 1999 May;105(2):388-93. Br J Haematol. 1999. PMID: 10233409 Free article.

2

Optimizing therapy for acute myeloid leukemia based on differences in intracellular metabolism of cytosine arabinoside between leukemic blasts and normal mononuclear blood cells.

Hiddemann W, Schleyer E, Unterhalt M, Kern W, Büchner T. Hiddemann W, et al. Among authors: schleyer e. Ther Drug Monit. 1996 Aug;18(4):341-9. doi: 10.1097/00007691-199608000-00005. Ther Drug Monit. 1996. PMID: 8857548

3

Cytidine deaminase - the methodological relevance of AraC deamination for ex vivo experiments using cultured cell lines, fresh leukemic blasts, and normal bone marrow cells.

Braess J, Pförtner J, Kern W, Hiddemann W, Schleyer E. Braess J, et al. Among authors: schleyer e. Ann Hematol. 1999 Nov;78(11):514-20. doi: 10.1007/s002770050548. Ann Hematol. 1999. PMID: 10602895

4

Successful modulation of high-dose cytosine arabinoside metabolism in acute myeloid leukaemia by haematopoietic growth factors: no effect of ribonucleotide reductase inhibitors fludarabine and gemcitabine.

Braess J, Wegendt C, Jahns-Streubel G, Kern W, Keye S, Unterhalt M, Schleyer E, Hiddemann W. Braess J, et al. Among authors: schleyer e. Br J Haematol. 2000 May;109(2):388-95. doi: 10.1046/j.1365-2141.2000.02056.x. Br J Haematol. 2000. PMID: 10848830 Free article.

5

The pharmacodynamic basis for the increased antileukaemic efficacy of cytosine arabinoside-based treatment regimens in acute myeloid leukaemia with a high proliferative activity.

Braess J, Voss S, Jahns-Streubel G, Schoch C, Haferlach T, Kern W, Keye S, Schleyer E, Hiddemann W. Braess J, et al. Among authors: schleyer e. Br J Haematol. 2000 Jul;110(1):170-9. doi: 10.1046/j.1365-2141.2000.02151.x. Br J Haematol. 2000. PMID: 10930995 Free article.

6

Proliferative activity of leukaemic blasts and cytosine arabinoside pharmacodynamics are associated with cytogenetically defined prognostic subgroups in acute myeloid leukaemia.

Braess J, Jahns-Streubel G, Schoch C, Haase D, Haferlach T, Fiegl M, Voss S, Kern W, Schleyer E, Hiddemann W. Braess J, et al. Among authors: schleyer e. Br J Haematol. 2001 Jun;113(4):975-82. doi: 10.1046/j.1365-2141.2001.02866.x. Br J Haematol. 2001. PMID: 11442492 Free article.

7

Detection and determination of the major metabolites of [3H]cytosine arabinoside by high-performance liquid chromatography.

Braess J, Pförtner J, Kaufmann CC, Ramsauer B, Unterhalt M, Hiddemann W, Schleyer E. Braess J, et al. Among authors: schleyer e. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):131-40. doi: 10.1016/0378-4347(95)00372-x. J Chromatogr B Biomed Appl. 1996. PMID: 8852053

8

High antileukemic activity of sequential high dose cytosine arabinoside and mitoxantrone in patients with refractory acute leukemias. Results of a clinical phase II study.

Kern W, Schleyer E, Unterhalt M, Wörmann B, Büchner T, Hiddemann W. Kern W, et al. Among authors: schleyer e. Cancer. 1997 Jan 1;79(1):59-68. Cancer. 1997. PMID: 8988727

9

Differential effect of GM-CSF pretreatment on intracellular Ara-C metabolism in normal bone marrow mononuclear cells vs acute myeloid leukemia (AML) blasts.

Reuter C, Schleyer E, Rolf C, Wörmann B, Büchner T, Hiddemann W. Reuter C, et al. Among authors: schleyer e. Leukemia. 1997 Apr;11(4):561-71. doi: 10.1038/sj.leu.2400613. Leukemia. 1997. PMID: 9096697

10

Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone (FIS-HAM) salvage therapy in highly resistant acute leukemias.

Kern W, Schleyer E, Braess J, Wittmer E, Ohnesorge J, Unterhalt M, Wörmann B, Büchner T, Hiddemann W. Kern W, et al. Among authors: schleyer e. Ann Hematol. 2001 Jun;80(6):334-9. doi: 10.1007/s002770100293. Ann Hematol. 2001. PMID: 11475146 Clinical Trial.

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