Guo Q - Search Results

1

Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.

Guo Q, Fu W, Holtsberg FW, Steiner SM, Mattson MP. Guo Q, et al. J Neurosci Res. 1999 Jun 1;56(5):457-70. doi: 10.1002/(SICI)1097-4547(19990601)56:5<457::AID-JNR2>3.0.CO;2-P. J Neurosci Res. 1999. PMID: 10369213

2

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP. Guo Q, et al. J Neurosci. 1997 Jun 1;17(11):4212-22. doi: 10.1523/JNEUROSCI.17-11-04212.1997. J Neurosci. 1997. PMID: 9151738 Free PMC article.

3

Nerve growth factor-independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1.

Pedersen WA, Guo Q, Hartman BK, Mattson MP. Pedersen WA, et al. Among authors: guo q. J Biol Chem. 1997 Sep 5;272(36):22397-400. doi: 10.1074/jbc.272.36.22397. J Biol Chem. 1997. PMID: 9278388 Free article.

4

Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?

Mattson MP, Guo Q. Mattson MP, et al. Among authors: guo q. J Neurosci Res. 1997 Nov 15;50(4):505-13. doi: 10.1002/(SICI)1097-4547(19971115)50:4<505::AID-JNR1>3.0.CO;2-I. J Neurosci Res. 1997. PMID: 9404712 Review.

5

Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.

Mattson MP, Guo Q, Furukawa K, Pedersen WA. Mattson MP, et al. Among authors: guo q. J Neurochem. 1998 Jan;70(1):1-14. doi: 10.1046/j.1471-4159.1998.70010001.x. J Neurochem. 1998. PMID: 9422341 Free article. Review.

6

Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.

Mattson MP, Robinson N, Guo Q. Mattson MP, et al. Among authors: guo q. Neuroreport. 1997 Dec 1;8(17):3817-21. doi: 10.1097/00001756-199712010-00031. Neuroreport. 1997. PMID: 9427376

7

Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells.

Kruman I, Guo Q, Mattson MP. Kruman I, et al. Among authors: guo q. J Neurosci Res. 1998 Feb 1;51(3):293-308. doi: 10.1002/(SICI)1097-4547(19980201)51:3<293::AID-JNR3>3.0.CO;2-B. J Neurosci Res. 1998. PMID: 9486765

8

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function.

Guo Q, Christakos S, Robinson N, Mattson MP. Guo Q, et al. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3227-32. doi: 10.1073/pnas.95.6.3227. Proc Natl Acad Sci U S A. 1998. PMID: 9501245 Free PMC article.

9

Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.

Guo Q, Robinson N, Mattson MP. Guo Q, et al. J Biol Chem. 1998 May 15;273(20):12341-51. doi: 10.1074/jbc.273.20.12341. J Biol Chem. 1998. PMID: 9575187 Free article.

10

Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.

Keller JN, Guo Q, Holtsberg FW, Bruce-Keller AJ, Mattson MP. Keller JN, et al. Among authors: guo q. J Neurosci. 1998 Jun 15;18(12):4439-50. doi: 10.1523/JNEUROSCI.18-12-04439.1998. J Neurosci. 1998. PMID: 9614221 Free PMC article.

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