Wedge SR - Search Results

1

ZD4190: an orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy.

Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Curwen JO, Hennequin LF, Thomas AP, Stokes ES, Curry B, Richmond GH, Wadsworth PF. Wedge SR, et al. Cancer Res. 2000 Feb 15;60(4):970-5. Cancer Res. 2000. PMID: 10706112

2

Phase I trial of temozolomide using an extended continuous oral schedule.

Brock CS, Newlands ES, Wedge SR, Bower M, Evans H, Colquhoun I, Roddie M, Glaser M, Brampton MH, Rustin GJ. Brock CS, et al. Among authors: wedge sr. Cancer Res. 1998 Oct 1;58(19):4363-7. Cancer Res. 1998. PMID: 9766665 Clinical Trial.

3

Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors.

Hennequin LF, Thomas AP, Johnstone C, Stokes ES, Plé PA, Lohmann JJ, Ogilvie DJ, Dukes M, Wedge SR, Curwen JO, Kendrew J, Lambert-van der Brempt C. Hennequin LF, et al. Among authors: wedge sr. J Med Chem. 1999 Dec 30;42(26):5369-89. doi: 10.1021/jm990345w. J Med Chem. 1999. PMID: 10639280

4

Inhibition of VEGF signal transduction. Identification of ZD4190.

Wedge SR, Ogilvie DJ. Wedge SR, et al. Adv Exp Med Biol. 2000;476:307-10. doi: 10.1007/978-1-4615-4221-6_25. Adv Exp Med Biol. 2000. PMID: 10949675 No abstract available.

5

Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors.

Hennequin LF, Stokes ES, Thomas AP, Johnstone C, Plé PA, Ogilvie DJ, Dukes M, Wedge SR, Kendrew J, Curwen JO. Hennequin LF, et al. Among authors: wedge sr. J Med Chem. 2002 Mar 14;45(6):1300-12. doi: 10.1021/jm011022e. J Med Chem. 2002. PMID: 11881999

6

Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling.

Gasmi A, Bourcier C, Aloui Z, Srairi N, Marchetti S, Gimond C, Wedge SR, Hennequin L, Pouysségur J. Gasmi A, et al. Among authors: wedge sr. J Biol Chem. 2002 Aug 16;277(33):29992-8. doi: 10.1074/jbc.M202202200. Epub 2002 May 20. J Biol Chem. 2002. PMID: 12021274 Free article.

7

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Chester R, Jackson JA, Boffey SJ, Valentine PJ, Curwen JO, Musgrove HL, Graham GA, Hughes GD, Thomas AP, Stokes ES, Curry B, Richmond GH, Wadsworth PF, Bigley AL, Hennequin LF. Wedge SR, et al. Cancer Res. 2002 Aug 15;62(16):4645-55. Cancer Res. 2002. PMID: 12183421

8

ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity.

Whittles CE, Pocock TM, Wedge SR, Kendrew J, Hennequin LF, Harper SJ, Bates DO. Whittles CE, et al. Among authors: wedge sr. Microcirculation. 2002 Dec;9(6):513-22. doi: 10.1038/sj.mn.7800164. Microcirculation. 2002. PMID: 12483548

9

Dynamic contrast-enhanced MRI of vascular changes induced by the VEGF-signalling inhibitor ZD4190 in human tumour xenografts.

Checkley D, Tessier JJ, Wedge SR, Dukes M, Kendrew J, Curry B, Middleton B, Waterton JC. Checkley D, et al. Among authors: wedge sr. Magn Reson Imaging. 2003 Jun;21(5):475-82. doi: 10.1016/s0730-725x(02)00644-6. Magn Reson Imaging. 2003. PMID: 12878256

10

Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signalling inhibitor, in PC-3 prostate tumours.

Checkley D, Tessier JJ, Kendrew J, Waterton JC, Wedge SR. Checkley D, et al. Among authors: wedge sr. Br J Cancer. 2003 Nov 17;89(10):1889-95. doi: 10.1038/sj.bjc.6601386. Br J Cancer. 2003. PMID: 14612898 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

92 results

Search Page

Filters