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Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.
Milush JM, Reeves JD, Gordon SN, Zhou D, Muthukumar A, Kosub DA, Chacko E, Giavedoni LD, Ibegbu CC, Cole KS, Miamidian JL, Paiardini M, Barry AP, Staprans SI, Silvestri G, Sodora DL. Milush JM, et al. Among authors: sodora dl. J Immunol. 2007 Sep 1;179(5):3047-56. doi: 10.4049/jimmunol.179.5.3047. J Immunol. 2007. PMID: 17709519
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.
Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G. Gordon SN, et al. Among authors: sodora dl. J Immunol. 2007 Sep 1;179(5):3026-34. doi: 10.4049/jimmunol.179.5.3026. J Immunol. 2007. PMID: 17709517 Free PMC article.
Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.
Milush JM, Mir KD, Sundaravaradan V, Gordon SN, Engram J, Cano CA, Reeves JD, Anton E, O'Neill E, Butler E, Hancock K, Cole KS, Brenchley JM, Else JG, Silvestri G, Sodora DL. Milush JM, et al. Among authors: sodora dl. J Clin Invest. 2011 Mar;121(3):1102-10. doi: 10.1172/JCI44876. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317533 Free PMC article.
97 results