Stratford IJ - Search Results

1

Cole C, Marks DS, Jaffar M, Stratford IJ, Douglas KT, Freeman S. Cole C, et al. Among authors: stratford ij. Anticancer Drug Des. 1999 Oct;14(5):411-20. Anticancer Drug Des. 1999. PMID: 10766296

2

Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.

Murray PE, McNally VA, Lockyer SD, Williams KJ, Stratford IJ, Jaffar M, Freeman S. Murray PE, et al. Among authors: stratford ij. Bioorg Med Chem. 2002 Mar;10(3):525-30. doi: 10.1016/s0968-0896(01)00309-1. Bioorg Med Chem. 2002. PMID: 11814838

3

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

Cole C, Reigan P, Gbaj A, Edwards PN, Douglas KT, Stratford IJ, Freeman S, Jaffar M. Cole C, et al. Among authors: stratford ij. J Med Chem. 2003 Jan 16;46(2):207-9. doi: 10.1021/jm020964w. J Med Chem. 2003. PMID: 12519058

4

Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.

Reigan P, Gbaj A, Chinje E, Stratford IJ, Douglas KT, Freeman S. Reigan P, et al. Among authors: stratford ij. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5247-50. doi: 10.1016/j.bmcl.2004.08.036. Bioorg Med Chem Lett. 2004. PMID: 15454205

5

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

Reigan P, Edwards PN, Gbaj A, Cole C, Barry ST, Page KM, Ashton SE, Luke RW, Douglas KT, Stratford IJ, Jaffar M, Bryce RA, Freeman S. Reigan P, et al. Among authors: stratford ij. J Med Chem. 2005 Jan 27;48(2):392-402. doi: 10.1021/jm049494r. J Med Chem. 2005. PMID: 15658853

6

Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.

McNally VA, Rajabi M, Gbaj A, Stratford IJ, Edwards PN, Douglas KT, Bryce RA, Jaffar M, Freeman S. McNally VA, et al. Among authors: stratford ij. J Pharm Pharmacol. 2007 Apr;59(4):537-47. doi: 10.1211/jpp.59.4.0008. J Pharm Pharmacol. 2007. PMID: 17430637

7

Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.

Reigan P, Gbaj A, Stratford IJ, Bryce RA, Freeman S. Reigan P, et al. Among authors: stratford ij. Eur J Med Chem. 2008 Jun;43(6):1248-60. doi: 10.1016/j.ejmech.2007.07.015. Epub 2007 Aug 6. Eur J Med Chem. 2008. PMID: 17870212

8

Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening.

McNally VA, Gbaj A, Douglas KT, Stratford IJ, Jaffar M, Freeman S, Bryce RA. McNally VA, et al. Among authors: stratford ij. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3705-9. doi: 10.1016/j.bmcl.2003.08.010. Bioorg Med Chem Lett. 2003. PMID: 14552762

9

5-substituted analogues of 3-hydroxymethyl-5-aziridinyl-1-methyl-2-[1H-indole-4,7-dione]prop-2-en- 1-ol (EO9, NSC 382459) and their regioisomers as hypoxia-selective agents: structure-cytotoxicity in vitro.

Jaffar M, Naylor MA, Robertson N, Lockyer SD, Phillips RM, Everett SA, Adams GE, Stratford IJ. Jaffar M, et al. Among authors: stratford ij. Anticancer Drug Des. 1998 Mar;13(2):105-23. Anticancer Drug Des. 1998. PMID: 9524554

10

Targeting hypoxia with a new generation of indolequinones.

Jaffar M, Naylor MA, Robertson N, Stratford IJ. Jaffar M, et al. Among authors: stratford ij. Anticancer Drug Des. 1998 Sep;13(6):593-609. Anticancer Drug Des. 1998. PMID: 9755720 Review.

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