Hutton M - Search Results

1

Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme.

Stracke JO, Hutton M, Stewart M, Pendás AM, Smith B, López-Otin C, Murphy G, Knäuper V. Stracke JO, et al. Among authors: hutton m. J Biol Chem. 2000 May 19;275(20):14809-16. doi: 10.1074/jbc.275.20.14809. J Biol Chem. 2000. PMID: 10809722 Free article.

2

The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations.

Butler GS, Hutton M, Wattam BA, Williamson RA, Knäuper V, Willenbrock F, Murphy G. Butler GS, et al. Among authors: hutton m. J Biol Chem. 1999 Jul 16;274(29):20391-6. doi: 10.1074/jbc.274.29.20391. J Biol Chem. 1999. PMID: 10400663 Free article.

3

Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14.

Williamson RA, Hutton M, Vogt G, Rapti M, Knäuper V, Carr MD, Murphy G. Williamson RA, et al. Among authors: hutton m. J Biol Chem. 2001 Aug 31;276(35):32966-70. doi: 10.1074/jbc.M101843200. Epub 2001 Jun 4. J Biol Chem. 2001. PMID: 11390386 Free article.

4

Matrix metalloproteinases in arthritic disease.

Murphy G, Knäuper V, Atkinson S, Butler G, English W, Hutton M, Stracke J, Clark I. Murphy G, et al. Among authors: hutton m. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S39-49. doi: 10.1186/ar572. Epub 2002 May 9. Arthritis Res. 2002. PMID: 12110122 Free PMC article. Review.

5

Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).

Worley JR, Thompkins PB, Lee MH, Hutton M, Soloway P, Edwards DR, Murphy G, Knäuper V. Worley JR, et al. Among authors: hutton m. Biochem J. 2003 Jun 15;372(Pt 3):799-809. doi: 10.1042/BJ20021573. Biochem J. 2003. PMID: 12630911 Free PMC article.

6

Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail.

Murphy G, Knäuper V, Lee MH, Amour A, Worley JR, Hutton M, Atkinson S, Rapti M, Williamson R. Murphy G, et al. Among authors: hutton m. Biochem Soc Symp. 2003;(70):65-80. doi: 10.1042/bss0700065. Biochem Soc Symp. 2003. PMID: 14587283 Review.

7

Kinetic analysis of the mechanism of interaction of full-length TIMP-2 and gelatinase A: evidence for the existence of a low-affinity intermediate.

Hutton M, Willenbrock F, Brocklehurst K, Murphy G. Hutton M, et al. Biochemistry. 1998 Jul 14;37(28):10094-8. doi: 10.1021/bi980616p. Biochemistry. 1998. PMID: 9665714

8

TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.

Amour A, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Stephens PE, Shelley C, Hutton M, Knäuper V, Docherty AJ, Murphy G. Amour A, et al. Among authors: hutton m. FEBS Lett. 1998 Sep 11;435(1):39-44. doi: 10.1016/s0014-5793(98)01031-x. FEBS Lett. 1998. PMID: 9755855 Free article.

9

Inhibition of the metalloproteinase domain of mouse TACE.

Amour A, Hutton M, Knäuper V, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Docherty AJ, Murphy G. Amour A, et al. Among authors: hutton m. Ann N Y Acad Sci. 1999 Jun 30;878:728-31. doi: 10.1111/j.1749-6632.1999.tb07774.x. Ann N Y Acad Sci. 1999. PMID: 10415820 No abstract available.

10

Analysis of the interaction of TIMP-2 and MMPs: engineering the changes.

Hutton M, Butler GS, Wattam BA, Willenbrock F, Williamson RA, Murphy G. Hutton M, et al. Ann N Y Acad Sci. 1999 Jun 30;878:524-7. doi: 10.1111/j.1749-6632.1999.tb07716.x. Ann N Y Acad Sci. 1999. PMID: 10415762 No abstract available.

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