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Page 1
Carbacyclic peptide mimetics as VCAM-VLA-4 antagonists.
Tilley J, Kaplan G, Fotouhi N, Wolitzky B, Rowan K. Tilley J, et al. Among authors: kaplan g. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1163-5. doi: 10.1016/s0960-894x(00)00173-6. Bioorg Med Chem Lett. 2000. PMID: 10866372
N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Hull K, Lou JP, Kaplan G, Sheffron A, Chen L, Campbell R, Guthrie R, Huang TN, Huby N, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: kaplan g. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2475-8. doi: 10.1016/s0960-894x(02)00386-4. Bioorg Med Chem Lett. 2002. PMID: 12161161
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Lou JP, Chen L, Kaplan G, Mennona F, Campbell R, Guthrie R, Huang TN, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: kaplan g. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82. doi: 10.1016/s0960-894x(02)00387-6. Bioorg Med Chem Lett. 2002. PMID: 12161162
N-benzylpyroglutamyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Chen L, Tilley JW, Guthrie RW, Mennona F, Huang TN, Kaplan G, Trilles R, Miklowski D, Huby N, Schwinge V, Wolitzky B, Rowan K. Chen L, et al. Among authors: kaplan g. Bioorg Med Chem Lett. 2000 Apr 17;10(8):729-33. doi: 10.1016/s0960-894x(00)00089-5. Bioorg Med Chem Lett. 2000. PMID: 10782674
Identification of N-acyl 4-(3-pyridonyl)phenylalanine derivatives and their orally active prodrug esters as dual acting α4β1 and α4β7 receptor antagonists.
Tilley JW, Sidduri A, Lou J, Kaplan G, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Tilley JW, et al. Among authors: kaplan g. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1036-40. doi: 10.1016/j.bmcl.2012.12.019. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312471
Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.
Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Chu XJ, et al. Among authors: kaplan g. J Med Chem. 2006 Nov 2;49(22):6549-60. doi: 10.1021/jm0606138. J Med Chem. 2006. PMID: 17064073
1,729 results