Schwartz TW - Search Results

1

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor.

Holst B, Elling CE, Schwartz TW. Holst B, et al. Among authors: schwartz tw. Mol Pharmacol. 2000 Aug;58(2):263-70. doi: 10.1124/mol.58.2.263. Mol Pharmacol. 2000. PMID: 10908293

2

Structure-function studies on neuropeptide Y and pancreatic polypeptide--evidence for two PP-fold receptors in vas deferens.

Jørgensen JC, Fuhlendorff J, Schwartz TW. Jørgensen JC, et al. Among authors: schwartz tw. Eur J Pharmacol. 1990 Sep 4;186(1):105-14. doi: 10.1016/0014-2999(90)94065-6. Eur J Pharmacol. 1990. PMID: 2178092

3

Conserved HisVI-17 of the NK-1 receptor is involved in binding of non-peptide antagonists but not substance P.

Zoffmann S, Gether U, Schwartz TW. Zoffmann S, et al. Among authors: schwartz tw. FEBS Lett. 1993 Dec 28;336(3):506-10. doi: 10.1016/0014-5793(93)80865-r. FEBS Lett. 1993. PMID: 7506676 Free article.

4

The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors.

Jensen CJ, Gerard NP, Schwartz TW, Gether U. Jensen CJ, et al. Among authors: schwartz tw. Mol Pharmacol. 1994 Feb;45(2):294-9. Mol Pharmacol. 1994. PMID: 7509441

5

Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.

Rosenkilde MM, Cahir M, Gether U, Hjorth SA, Schwartz TW. Rosenkilde MM, et al. Among authors: schwartz tw. J Biol Chem. 1994 Nov 11;269(45):28160-4. J Biol Chem. 1994. PMID: 7525569 Free article.

6

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

Elling CE, Nielsen SM, Schwartz TW. Elling CE, et al. Among authors: schwartz tw. Nature. 1995 Mar 2;374(6517):74-7. doi: 10.1038/374074a0. Nature. 1995. PMID: 7532789

7

Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine.

Hjorth SA, Thirstrup K, Grandy DK, Schwartz TW. Hjorth SA, et al. Among authors: schwartz tw. Mol Pharmacol. 1995 Jun;47(6):1089-94. Mol Pharmacol. 1995. PMID: 7541509

8

Chimeric NK1 (substance P)/NK3 (neurokinin B) receptors. Identification of domains determining the binding specificity of tachykinin agonists.

Gether U, Johansen TE, Schwartz TW. Gether U, et al. Among authors: schwartz tw. J Biol Chem. 1993 Apr 15;268(11):7893-8. J Biol Chem. 1993. PMID: 7681831 Free article.

9

Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors.

Gether U, Yokota Y, Emonds-Alt X, Brelière JC, Lowe JA 3rd, Snider RM, Nakanishi S, Schwartz TW. Gether U, et al. Among authors: schwartz tw. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6194-8. doi: 10.1073/pnas.90.13.6194. Proc Natl Acad Sci U S A. 1993. PMID: 7687062 Free PMC article.

10

Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.

Schambye HT, Hjorth SA, Weinstock J, Schwartz TW. Schambye HT, et al. Among authors: schwartz tw. Mol Pharmacol. 1995 Mar;47(3):425-31. Mol Pharmacol. 1995. PMID: 7700239

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