Kelland LR - Search Results

1

Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines.

Gregson SJ, Howard PW, Corcoran KE, Barcella S, Yasin MM, Hurst AA, Jenkins TC, Kelland LR, Thurston DE. Gregson SJ, et al. Among authors: kelland lr. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1845-7. doi: 10.1016/s0960-894x(00)00351-6. Bioorg Med Chem Lett. 2000. PMID: 10969982

2

Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines.

Thurston DE, Bose DS, Howard PW, Jenkins TC, Leoni A, Baraldi PG, Guiotto A, Cacciari B, Kelland LR, Foloppe MP, Rault S. Thurston DE, et al. Among authors: kelland lr. J Med Chem. 1999 Jun 3;42(11):1951-64. doi: 10.1021/jm981117p. J Med Chem. 1999. PMID: 10354403

3

Design, synthesis, and evaluation of a novel sequence-selective epoxide-containing DNA cross-linking agent based on the pyrrolo[2, 1-c][1,4]benzodiazepine system.

Wilson SC, Howard PW, Forrow SM, Hartley JA, Adams LJ, Jenkins TC, Kelland LR, Thurston DE. Wilson SC, et al. Among authors: kelland lr. J Med Chem. 1999 Oct 7;42(20):4028-41. doi: 10.1021/jm981124d. J Med Chem. 1999. PMID: 10514273

4

Effect of C2/C3-endo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines.

Gregson SJ, Howard PW, Barcella S, Nakamya A, Jenkins TC, Kelland LR, Thurston DE. Gregson SJ, et al. Among authors: kelland lr. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1849-51. doi: 10.1016/s0960-894x(00)00350-4. Bioorg Med Chem Lett. 2000. PMID: 10969983

5

Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity.

Gregson SJ, Howard PW, Hartley JA, Brooks NA, Adams LJ, Jenkins TC, Kelland LR, Thurston DE. Gregson SJ, et al. Among authors: kelland lr. J Med Chem. 2001 Mar 1;44(5):737-48. doi: 10.1021/jm001064n. J Med Chem. 2001. PMID: 11262084

6

Synthesis of the first example of a C2-C3/C2'-C3'-endo unsaturated pyrrolo[2,1-c][1,4]benzodiazepine dimer.

Gregson SJ, Howard PW, Corcoran KE, Jenkins TC, Kelland LR, Thurston DE. Gregson SJ, et al. Among authors: kelland lr. Bioorg Med Chem Lett. 2001 Nov 5;11(21):2859-62. doi: 10.1016/s0960-894x(01)00560-1. Bioorg Med Chem Lett. 2001. PMID: 11597416

7

Synthesis and biological evaluation of an N10-Psec substituted pyrrolo[2,1-c][1,4]benzodiazepine prodrug.

Berry JM, Howard PW, Kelland LR, Thurston DE. Berry JM, et al. Among authors: kelland lr. Bioorg Med Chem Lett. 2002 May 20;12(10):1413-6. doi: 10.1016/s0960-894x(02)00150-6. Bioorg Med Chem Lett. 2002. PMID: 11992788

8

Preclinical pharmacology and antitumour activity of the novel sequence-selective DNA minor-groove cross-linking agent DSB-120.

Walton MI, Goddard P, Kelland LR, Thurston DE, Harrap KR. Walton MI, et al. Among authors: kelland lr. Cancer Chemother Pharmacol. 1996;38(5):431-8. doi: 10.1007/s002800050507. Cancer Chemother Pharmacol. 1996. PMID: 8765436

9

Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones.

Perry PJ, Reszka AP, Wood AA, Read MA, Gowan SM, Dosanjh HS, Trent JO, Jenkins TC, Kelland LR, Neidle S. Perry PJ, et al. Among authors: kelland lr. J Med Chem. 1998 Nov 19;41(24):4873-84. doi: 10.1021/jm981067o. J Med Chem. 1998. PMID: 9822556

10

1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation.

Antonini I, Polucci P, Jenkins TC, Kelland LR, Menta E, Pescalli N, Stefanska B, Mazerski J, Martelli S. Antonini I, et al. Among authors: kelland lr. J Med Chem. 1997 Nov 7;40(23):3749-55. doi: 10.1021/jm970114u. J Med Chem. 1997. PMID: 9371240

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

206 results

Search Page

Filters