Meltzer LT - Search Results

1

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(heteroarylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Kesten SR, Boxer PA, Serpa KA, Meltzer LT, Wise LD, Espitia SA, Konkoy CS, Whittemore ER, Woodward RM. Wright JL, et al. Among authors: meltzer lt. J Med Chem. 2000 Sep 7;43(18):3408-19. doi: 10.1021/jm000023o. J Med Chem. 2000. PMID: 10978188

2

Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues.

Kornberg BE, Nikam SS, Wright JL, Kesten SR, Meltzer LT, Coughenour L, Barr B, Serpa KA, McCormick J. Kornberg BE, et al. Among authors: meltzer lt. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1213-6. doi: 10.1016/j.bmcl.2003.12.049. Bioorg Med Chem Lett. 2004. PMID: 14980668

3

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Bigge CF, Boxer PA, Serpa K, Meltzer LT, Wise LD, Cai SX, Hawkinson JE, Konkoy CS, Whittemore ER, Woodward RM, Zhou ZL. Wright JL, et al. Among authors: meltzer lt. J Med Chem. 1999 Jul 1;42(13):2469-77. doi: 10.1021/jm990148x. J Med Chem. 1999. PMID: 10395488

4

Discovery of subtype-selective NMDA receptor ligands: 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists.

Wright JL, Gregory TF, Boxer PA, Meltzer LT, Serpa KA, Wise LD. Wright JL, et al. Among authors: meltzer lt. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2815-8. doi: 10.1016/s0960-894x(99)00482-5. Bioorg Med Chem Lett. 1999. PMID: 10522697

5

Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.

Gregory TF, Wright JL, Wise LD, Meltzer LT, Serpa KA, Konkoy CS, Whittemore ER, Woodward RM. Gregory TF, et al. Among authors: meltzer lt. Bioorg Med Chem Lett. 2000 Mar 20;10(6):527-9. doi: 10.1016/s0960-894x(00)00035-4. Bioorg Med Chem Lett. 2000. PMID: 10741546

6

Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements.

Schelkun RM, Yuen PW, Serpa K, Meltzer LT, Wise LD, Whittemore ER, Woodward RM. Schelkun RM, et al. Among authors: meltzer lt. J Med Chem. 2000 May 4;43(9):1892-7. doi: 10.1021/jm990537r. J Med Chem. 2000. PMID: 10794706

7

Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones.

Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT. Jaen JC, et al. Among authors: meltzer lt. J Med Chem. 1991 Jan;34(1):248-56. doi: 10.1021/jm00105a039. J Med Chem. 1991. PMID: 1671416

8

Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907).

van Vliet LA, Rodenhuis N, Dijkstra D, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Sundell S, Lundmark M. van Vliet LA, et al. Among authors: meltzer lt. J Med Chem. 2000 Jul 27;43(15):2871-82. doi: 10.1021/jm0000113. J Med Chem. 2000. PMID: 10956195

9

Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists.

van Vliet LA, Rodenhuis N, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Haenen GR, Bast A. van Vliet LA, et al. Among authors: meltzer lt. J Med Chem. 2000 Sep 21;43(19):3549-57. doi: 10.1021/jm000087z. J Med Chem. 2000. PMID: 11000009

10

Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Wikström HV. Venhuis BJ, et al. Among authors: meltzer lt. J Med Chem. 2003 Sep 11;46(19):4136-40. doi: 10.1021/jm0307786. J Med Chem. 2003. PMID: 12954065

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