Wise LD - Search Results

1

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(heteroarylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Kesten SR, Boxer PA, Serpa KA, Meltzer LT, Wise LD, Espitia SA, Konkoy CS, Whittemore ER, Woodward RM. Wright JL, et al. Among authors: wise ld. J Med Chem. 2000 Sep 7;43(18):3408-19. doi: 10.1021/jm000023o. J Med Chem. 2000. PMID: 10978188

2

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Bigge CF, Boxer PA, Serpa K, Meltzer LT, Wise LD, Cai SX, Hawkinson JE, Konkoy CS, Whittemore ER, Woodward RM, Zhou ZL. Wright JL, et al. Among authors: wise ld. J Med Chem. 1999 Jul 1;42(13):2469-77. doi: 10.1021/jm990148x. J Med Chem. 1999. PMID: 10395488

3

4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.

Zhou ZL, Cai SX, Whittemore ER, Konkoy CS, Espitia SA, Tran M, Rock DM, Coughenour LL, Hawkinson JE, Boxer PA, Bigge CF, Wise LD, Weber E, Woodward RM, Keana JF. Zhou ZL, et al. Among authors: wise ld. J Med Chem. 1999 Jul 29;42(15):2993-3000. doi: 10.1021/jm990246i. J Med Chem. 1999. PMID: 10425109

4

Design, synthesis, and evaluation of chromen-2-ones as potent and selective human dopamine D4 antagonists.

Kesten SR, Heffner TG, Johnson SJ, Pugsley TA, Wright JL, Wise LD. Kesten SR, et al. Among authors: wise ld. J Med Chem. 1999 Sep 9;42(18):3718-25. doi: 10.1021/jm990266k. J Med Chem. 1999. PMID: 10479303

5

Discovery of subtype-selective NMDA receptor ligands: 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists.

Wright JL, Gregory TF, Boxer PA, Meltzer LT, Serpa KA, Wise LD. Wright JL, et al. Among authors: wise ld. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2815-8. doi: 10.1016/s0960-894x(99)00482-5. Bioorg Med Chem Lett. 1999. PMID: 10522697

6

Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.

Gregory TF, Wright JL, Wise LD, Meltzer LT, Serpa KA, Konkoy CS, Whittemore ER, Woodward RM. Gregory TF, et al. Among authors: wise ld. Bioorg Med Chem Lett. 2000 Mar 20;10(6):527-9. doi: 10.1016/s0960-894x(00)00035-4. Bioorg Med Chem Lett. 2000. PMID: 10741546

7

Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements.

Schelkun RM, Yuen PW, Serpa K, Meltzer LT, Wise LD, Whittemore ER, Woodward RM. Schelkun RM, et al. Among authors: wise ld. J Med Chem. 2000 May 4;43(9):1892-7. doi: 10.1021/jm990537r. J Med Chem. 2000. PMID: 10794706

8

3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.

Konkel MJ, Lagu B, Boteju LW, Jimenez H, Noble S, Walker MW, Chandrasena G, Blackburn TP, Nikam SS, Wright JL, Kornberg BE, Gregory T, Pugsley TA, Akunne H, Zoski K, Wise LD. Konkel MJ, et al. Among authors: wise ld. J Med Chem. 2006 Jun 29;49(13):3757-8. doi: 10.1021/jm060001n. J Med Chem. 2006. PMID: 16789730

9

Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones.

Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT. Jaen JC, et al. Among authors: wise ld. J Med Chem. 1991 Jan;34(1):248-56. doi: 10.1021/jm00105a039. J Med Chem. 1991. PMID: 1671416

10

Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907).

van Vliet LA, Rodenhuis N, Dijkstra D, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Sundell S, Lundmark M. van Vliet LA, et al. Among authors: wise ld. J Med Chem. 2000 Jul 27;43(15):2871-82. doi: 10.1021/jm0000113. J Med Chem. 2000. PMID: 10956195

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