Vickers TA - Search Results

1

Discovery and analysis of antisense oligonucleotide activity in cell culture.

Baker BF, Condon TP, Koller E, McKay RA, Siwkowski AM, Vickers TA, Monia BP. Baker BF, et al. Among authors: vickers ta. Methods. 2001 Feb;23(2):191-8. doi: 10.1006/meth.2000.1120. Methods. 2001. PMID: 11181038 Review.

2

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis.

Vickers TA, Koo S, Bennett CF, Crooke ST, Dean NM, Baker BF. Vickers TA, et al. J Biol Chem. 2003 Feb 28;278(9):7108-18. doi: 10.1074/jbc.M210326200. Epub 2002 Dec 23. J Biol Chem. 2003. PMID: 12500975 Free article.

3

Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue.

Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, Kinberger GA. Wancewicz EV, et al. Among authors: vickers ta. J Med Chem. 2010 May 27;53(10):3919-26. doi: 10.1021/jm901489k. J Med Chem. 2010. PMID: 20420385 Free PMC article.

4

Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element.

Vickers T, Baker BF, Cook PD, Zounes M, Buckheit RW Jr, Germany J, Ecker DJ. Vickers T, et al. Nucleic Acids Res. 1991 Jun 25;19(12):3359-68. doi: 10.1093/nar/19.12.3359. Nucleic Acids Res. 1991. PMID: 2062653 Free PMC article.

5

Positional effect of chemical modifications on short interference RNA activity in mammalian cells.

Prakash TP, Allerson CR, Dande P, Vickers TA, Sioufi N, Jarres R, Baker BF, Swayze EE, Griffey RH, Bhat B. Prakash TP, et al. Among authors: vickers ta. J Med Chem. 2005 Jun 30;48(13):4247-53. doi: 10.1021/jm050044o. J Med Chem. 2005. PMID: 15974578

6

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.

Hua Y, Vickers TA, Baker BF, Bennett CF, Krainer AR. Hua Y, et al. Among authors: vickers ta. PLoS Biol. 2007 Apr;5(4):e73. doi: 10.1371/journal.pbio.0050073. PLoS Biol. 2007. PMID: 17355180 Free PMC article.

7

Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.

Vickers TA, Freier SM, Bui HH, Watt A, Crooke ST. Vickers TA, et al. PLoS One. 2014 Oct 15;9(10):e110615. doi: 10.1371/journal.pone.0110615. eCollection 2014. PLoS One. 2014. PMID: 25334092 Free PMC article.

8

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA.

Vickers TA, Crooke ST. Vickers TA, et al. Nucleic Acids Res. 2015 Oct 15;43(18):8955-63. doi: 10.1093/nar/gkv920. Epub 2015 Sep 17. Nucleic Acids Res. 2015. PMID: 26384424 Free PMC article.

9

Modification of MyD88 mRNA splicing and inhibition of IL-1beta signaling in cell culture and in mice with a 2'-O-methoxyethyl-modified oligonucleotide.

Vickers TA, Zhang H, Graham MJ, Lemonidis KM, Zhao C, Dean NM. Vickers TA, et al. J Immunol. 2006 Mar 15;176(6):3652-61. doi: 10.4049/jimmunol.176.6.3652. J Immunol. 2006. PMID: 16517734

10

Defining the factors that contribute to on-target specificity of antisense oligonucleotides.

Lima WF, Vickers TA, Nichols J, Li C, Crooke ST. Lima WF, et al. Among authors: vickers ta. PLoS One. 2014 Jul 29;9(7):e101752. doi: 10.1371/journal.pone.0101752. eCollection 2014. PLoS One. 2014. PMID: 25072142 Free PMC article.

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