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A single aromatic amino acid at the carboxyl terminus of Helicobacter pylori {alpha}1,3/4 fucosyltransferase determines substrate specificity.
Ma B, Lau LH, Palcic MM, Hazes B, Taylor DE. Ma B, et al. Among authors: hazes b. J Biol Chem. 2005 Nov 4;280(44):36848-56. doi: 10.1074/jbc.M504415200. Epub 2005 Sep 2. J Biol Chem. 2005. PMID: 16150700 Free article.
In contrast, FucT from strain NCTC11639 has exclusive alpha1,3 activity. Our domain swapping study (Ma, B., Wang, G., Palcic, M. M., Hazes, B., and Taylor, D. E. (2003) J. Biol. Chem. 278, 21893-21900) demonstrated that exchange of the hypervariable loops, (3 …
In contrast, FucT from strain NCTC11639 has exclusive alpha1,3 activity. Our domain swapping study (Ma, B., Wang, G., Palcic, M. M., …
54 results