Langer R - Search Results

1

Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library.

Lynn DM, Anderson DG, Putnam D, Langer R. Lynn DM, et al. Among authors: langer r. J Am Chem Soc. 2001 Aug 22;123(33):8155-6. doi: 10.1021/ja016288p. J Am Chem Soc. 2001. PMID: 11506588 No abstract available.

2

PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization.

Ando S, Putnam D, Pack DW, Langer R. Ando S, et al. Among authors: langer r. J Pharm Sci. 1999 Jan;88(1):126-30. doi: 10.1021/js9801687. J Pharm Sci. 1999. PMID: 9874713

3

Design of imidazole-containing endosomolytic biopolymers for gene delivery.

Pack DW, Putnam D, Langer R. Pack DW, et al. Among authors: langer r. Biotechnol Bioeng. 2000 Jan 20;67(2):217-23. Biotechnol Bioeng. 2000. PMID: 10592519

4

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini.

Putnam D, Gentry CA, Pack DW, Langer R. Putnam D, et al. Among authors: langer r. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1200-5. doi: 10.1073/pnas.98.3.1200. Epub 2001 Jan 23. Proc Natl Acad Sci U S A. 2001. PMID: 11158617 Free PMC article.

5

pH-Responsive Polymer Microspheres: Rapid Release of Encapsulated Material within the Range of Intracellular pH Financial support was provided by the NSF (Cooperative Agreement No. ECC9843342 to the MIT Biotechnology Process Engineering Center), the NIH (GM26698), and the Department of the Army (Cooperative Agreement DAMD 17-99-2-9-001 to the Center for Innovative Minimally Invasive Therapy). D.M.L. wishes to thank the NIH for a Postdoctoral Fellowship (NRSA Fellowship No. 1 F32 GM20227-01). Scanning electron microscopy and confocal microscopy images were acquired by William Fowle at the Northeastern University Center for Electron Microscopy. Dr. David Putnam, David Ting, and Tommy Thomas are thanked for helpful discussions.

Lynn DM, Amiji MM, Langer R. Lynn DM, et al. Among authors: langer r. Angew Chem Int Ed Engl. 2001 May 4;40(9):1707-1710. Angew Chem Int Ed Engl. 2001. PMID: 11353487 No abstract available.

6

Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA.

Perez C, Sanchez A, Putnam D, Ting D, Langer R, Alonso MJ. Perez C, et al. Among authors: langer r. J Control Release. 2001 Jul 10;75(1-2):211-24. doi: 10.1016/s0168-3659(01)00397-2. J Control Release. 2001. PMID: 11451511

7

Aliphatic ionenes as gene delivery agents: elucidation of structure-function relationship through modification of charge density and polymer length.

Zelikin AN, Putnam D, Shastri P, Langer R, Izumrudov VA. Zelikin AN, et al. Among authors: langer r. Bioconjug Chem. 2002 May-Jun;13(3):548-53. doi: 10.1021/bc015553t. Bioconjug Chem. 2002. PMID: 12009945

8

Moving smaller in drug discovery and delivery.

LaVan DA, Lynn DM, Langer R. LaVan DA, et al. Among authors: langer r. Nat Rev Drug Discov. 2002 Jan;1(1):77-84. doi: 10.1038/nrd707. Nat Rev Drug Discov. 2002. PMID: 12119612 Review.

9

Erodible conducting polymers for potential biomedical applications.

Zelikin AN, Lynn DM, Farhadi J, Martin I, Shastri V, Langer R. Zelikin AN, et al. Among authors: langer r. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):141-4. doi: 10.1002/1521-3773(20020104)41:1<141::aid-anie141>3.0.co;2-v. Angew Chem Int Ed Engl. 2002. PMID: 12491465 No abstract available.

10

Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive biodegradable system for paclitaxel delivery.

Potineni A, Lynn DM, Langer R, Amiji MM. Potineni A, et al. Among authors: langer r. J Control Release. 2003 Jan 17;86(2-3):223-34. doi: 10.1016/s0168-3659(02)00374-7. J Control Release. 2003. PMID: 12526819

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