Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis.
Machover D, Zittoun J, Saffroy R, Broët P, Giraudier S, Magnaldo T, Goldschmidt E, Debuire B, Orrico M, Tan Y, Mishal Z, Chevallier O, Tonetti C, Jouault H, Ulusakarya A, Tanguy ML, Metzger G, Hoffman RM.
Machover D, et al. Among authors: debuire b.
Cancer Res. 2002 Aug 15;62(16):4685-9.
Cancer Res. 2002.
PMID: 12183426