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A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels.
M'Barek S, Lopez-Gonzalez I, Andreotti N, di Luccio E, Visan V, Grissmer S, Judge S, El Ayeb M, Darbon H, Rochat H, Sampieri F, Béraud E, Fajloun Z, De Waard M, Sabatier JM. M'Barek S, et al. Among authors: rochat h. J Biol Chem. 2003 Aug 15;278(33):31095-104. doi: 10.1074/jbc.M304271200. Epub 2003 Jun 3. J Biol Chem. 2003. PMID: 12783861 Free article.
Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels.
Jouirou B, Mosbah A, Visan V, Grissmer S, M'Barek S, Fajloun Z, Van Rietschoten J, Devaux C, Rochat H, Lippens G, El Ayeb M, De Waard M, Mabrouk K, Sabatier JM. Jouirou B, et al. Among authors: rochat h. Biochem J. 2004 Jan 1;377(Pt 1):37-49. doi: 10.1042/BJ20030977. Biochem J. 2004. PMID: 14498829 Free PMC article.
Synthesis, 1H NMR structure, and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins.
Fajloun Z, Ferrat G, Carlier E, Fathallah M, Lecomte C, Sandoz G, di Luccio E, Mabrouk K, Legros C, Darbon H, Rochat H, Sabatier JM, De Waard M. Fajloun Z, et al. Among authors: rochat h. J Biol Chem. 2000 May 5;275(18):13605-12. doi: 10.1074/jbc.275.18.13605. J Biol Chem. 2000. PMID: 10788477 Free article.
256 results