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Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.
Yoshikawa T, Shimano H, Yahagi N, Ide T, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Takahashi A, Sone H, Osuga Ji J, Gotoda T, Ishibashi S, Yamada N. Yoshikawa T, et al. J Biol Chem. 2002 Jan 18;277(3):1705-11. doi: 10.1074/jbc.M105711200. Epub 2001 Nov 2. J Biol Chem. 2002. PMID: 11694526 Free article.
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.
Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N. Yoshikawa T, et al. Mol Endocrinol. 2003 Jul;17(7):1240-54. doi: 10.1210/me.2002-0190. Epub 2003 May 1. Mol Endocrinol. 2003. PMID: 12730331
High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.
Najima Y, Yahagi N, Takeuchi Y, Matsuzaka T, Sekiya M, Nakagawa Y, Amemiya-Kudo M, Okazaki H, Okazaki S, Tamura Y, Iizuka Y, Ohashi K, Harada K, Gotoda T, Nagai R, Kadowaki T, Ishibashi S, Yamada N, Osuga J, Shimano H. Najima Y, et al. Among authors: amemiya kudo m. J Biol Chem. 2005 Jul 29;280(30):27523-32. doi: 10.1074/jbc.m414549200. J Biol Chem. 2005. PMID: 16040616 Free article.
24 results