Karpuj MV - Search Results

1

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine.

Karpuj MV, Becher MW, Springer JE, Chabas D, Youssef S, Pedotti R, Mitchell D, Steinman L. Karpuj MV, et al. Nat Med. 2002 Feb;8(2):143-9. doi: 10.1038/nm0202-143. Nat Med. 2002. PMID: 11821898

2

Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications.

Karpuj MV, Becher MW, Steinman L. Karpuj MV, et al. Neurochem Int. 2002 Jan;40(1):31-6. doi: 10.1016/s0197-0186(01)00060-2. Neurochem Int. 2002. PMID: 11738470 Review.

3

An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide.

Pedotti R, Mitchell D, Wedemeyer J, Karpuj M, Chabas D, Hattab EM, Tsai M, Galli SJ, Steinman L. Pedotti R, et al. Nat Immunol. 2001 Mar;2(3):216-22. doi: 10.1038/85266. Nat Immunol. 2001. PMID: 11224520

4

The multifaceted role of transglutaminase in neurodegeneration: review article.

Karpuj M, Steinman L. Karpuj M, et al. Amino Acids. 2004 Jul;26(4):373-9. doi: 10.1007/s00726-004-0082-8. Epub 2004 Jul 6. Amino Acids. 2004. PMID: 15290343 Review.

5

Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei.

Karpuj MV, Garren H, Slunt H, Price DL, Gusella J, Becher MW, Steinman L. Karpuj MV, et al. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7388-93. doi: 10.1073/pnas.96.13.7388. Proc Natl Acad Sci U S A. 1999. PMID: 10377424 Free PMC article.

6

Idiotypic immunization induces immunity to mutated p53 and tumor rejection.

Ruiz PJ, Wolkowicz R, Waisman A, Hirschberg DL, Carmi P, Erez N, Garren H, Herkel J, Karpuj M, Steinman L, Rotter V, Cohen IR. Ruiz PJ, et al. Nat Med. 1998 Jun;4(6):710-2. doi: 10.1038/nm0698-710. Nat Med. 1998. PMID: 9623981

7

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease.

Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. Chabas D, et al. Science. 2001 Nov 23;294(5547):1731-5. doi: 10.1126/science.1062960. Science. 2001. PMID: 11721059

8

Suppressive immunization with DNA encoding a self-peptide prevents autoimmune disease: modulation of T cell costimulation.

Ruiz PJ, Garren H, Ruiz IU, Hirschberg DL, Nguyen LV, Karpuj MV, Cooper MT, Mitchell DJ, Fathman CG, Steinman L. Ruiz PJ, et al. Among authors: karpuj mv. J Immunol. 1999 Mar 15;162(6):3336-41. J Immunol. 1999. PMID: 10092787

9

Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis.

Ruiz PJ, Garren H, Hirschberg DL, Langer-Gould AM, Levite M, Karpuj MV, Southwood S, Sette A, Conlon P, Steinman L. Ruiz PJ, et al. Among authors: karpuj mv. J Exp Med. 1999 Apr 19;189(8):1275-84. doi: 10.1084/jem.189.8.1275. J Exp Med. 1999. PMID: 10209044 Free PMC article.

10

Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration.

van Strien ME, de Vries HE, Chrobok NL, Bol JGJM, Breve JJP, van der Pol SMP, Kooij G, van Buul JD, Karpuj M, Steinman L, Wilhelmus MM, Sestito C, Drukarch B, Van Dam AM. van Strien ME, et al. Brain Behav Immun. 2015 Nov;50:141-154. doi: 10.1016/j.bbi.2015.06.023. Epub 2015 Jun 29. Brain Behav Immun. 2015. PMID: 26133787

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