Hugill A - Search Results

1

A gene-driven approach to the identification of ENU mutants in the mouse.

Coghill EL, Hugill A, Parkinson N, Davison C, Glenister P, Clements S, Hunter J, Cox RD, Brown SD. Coghill EL, et al. Among authors: hugill a. Nat Genet. 2002 Mar;30(3):255-6. doi: 10.1038/ng847. Epub 2002 Feb 19. Nat Genet. 2002. PMID: 11850622

2

ENU mutagenesis in the mouse: application to human genetic disease.

Nolan PM, Hugill A, Cox RD. Nolan PM, et al. Among authors: hugill a. Brief Funct Genomic Proteomic. 2002 Oct;1(3):278-89. doi: 10.1093/bfgp/1.3.278. Brief Funct Genomic Proteomic. 2002. PMID: 15239894 Review.

3

A gene-driven ENU-based approach to generating an allelic series in any gene.

Quwailid MM, Hugill A, Dear N, Vizor L, Wells S, Horner E, Fuller S, Weedon J, McMath H, Woodman P, Edwards D, Campbell D, Rodger S, Carey J, Roberts A, Glenister P, Lalanne Z, Parkinson N, Coghill EL, McKeone R, Cox S, Willan J, Greenfield A, Keays D, Brady S, Spurr N, Gray I, Hunter J, Brown SD, Cox RD. Quwailid MM, et al. Among authors: hugill a. Mamm Genome. 2004 Aug;15(8):585-91. doi: 10.1007/s00335-004-2379-z. Mamm Genome. 2004. PMID: 15457338

4

A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.

Toye AA, Moir L, Hugill A, Bentley L, Quarterman J, Mijat V, Hough T, Goldsworthy M, Haynes A, Hunter AJ, Browne M, Spurr N, Cox RD. Toye AA, et al. Among authors: hugill a. Diabetes. 2004 Jun;53(6):1577-83. doi: 10.2337/diabetes.53.6.1577. Diabetes. 2004. PMID: 15161764

5

Contrasting effects of ENU induced embryonic lethal mutations of the quaking gene.

Cox RD, Hugill A, Shedlovsky A, Noveroske JK, Best S, Justice MJ, Lehrach H, Dove WF. Cox RD, et al. Among authors: hugill a. Genomics. 1999 May 1;57(3):333-41. doi: 10.1006/geno.1999.5804. Genomics. 1999. PMID: 10328999

6

A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse.

Hugill A, Shimomura K, Ashcroft FM, Cox RD. Hugill A, et al. Diabetologia. 2010 Nov;53(11):2352-6. doi: 10.1007/s00125-010-1866-x. Epub 2010 Aug 8. Diabetologia. 2010. PMID: 20694718 Free PMC article.

7

Islet Insulin Secretion Measurements in the Mouse.

Hugill A, Shimomura K, Cox RD. Hugill A, et al. Curr Protoc Mouse Biol. 2016 Sep 1;6(3):256-271. doi: 10.1002/cpmo.14. Curr Protoc Mouse Biol. 2016. PMID: 27584553

8

Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD. Freeman HC, et al. Among authors: hugill a. Diabetes. 2006 Jul;55(7):2153-6. doi: 10.2337/db06-0358. Diabetes. 2006. PMID: 16804088

9

Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides.

Cox R, Bouzekri N, Martin S, Southam L, Hugill A, Golamaully M, Cooper R, Adeyemo A, Soubrier F, Ward R, Lathrop GM, Matsuda F, Farrall M. Cox R, et al. Among authors: hugill a. Hum Mol Genet. 2002 Nov 1;11(23):2969-77. doi: 10.1093/hmg/11.23.2969. Hum Mol Genet. 2002. PMID: 12393808

10

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD. Goldsworthy M, et al. Among authors: hugill a. Diabetes. 2008 Aug;57(8):2234-44. doi: 10.2337/db07-0337. Epub 2008 May 13. Diabetes. 2008. PMID: 18477811 Free PMC article.

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