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Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A. Di Gennaro E, et al. Among authors: barbarino m. J Cell Physiol. 2003 Apr;195(1):139-50. doi: 10.1002/jcp.10239. J Cell Physiol. 2003. PMID: 12599217
Anti-cancer activity of dose-fractioned mPE +/- bevacizumab regimen is paralleled by immune-modulation in advanced squamous NSLC patients.
Pastina P, Nardone V, Croci S, Battaglia G, Vanni F, Bellan C, Barbarino M, Ricci V, Costantini S, Capone F, Botta C, Zarone MR, Misso G, Boccellino M, Caraglia M, Giordano A, Paladini P, Tassone P, Tagliaferri P, Cusi MG, Pirtoli L, Correale P. Pastina P, et al. Among authors: barbarino m. J Thorac Dis. 2017 Sep;9(9):3123-3131. doi: 10.21037/jtd.2017.08.68. J Thorac Dis. 2017. PMID: 29221287 Free PMC article.
Flavopiridol: An Old Drug With New Perspectives? Implication for Development of New Drugs.
Cimini A, d'Angelo M, Benedetti E, D'Angelo B, Laurenti G, Antonosante A, Cristiano L, Di Mambro A, Barbarino M, Castelli V, Cinque B, Cifone MG, Ippoliti R, Pentimalli F, Giordano A. Cimini A, et al. Among authors: barbarino m. J Cell Physiol. 2017 Feb;232(2):312-322. doi: 10.1002/jcp.25421. Epub 2016 Jun 2. J Cell Physiol. 2017. PMID: 27171480
Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold.
Giannini G, Battistuzzi G, Vesci L, Milazzo FM, De Paolis F, Barbarino M, Guglielmi MB, Carollo V, Gallo G, Artali R, Dallavalle S. Giannini G, et al. Among authors: barbarino m. Bioorg Med Chem Lett. 2014 Jan 15;24(2):462-6. doi: 10.1016/j.bmcl.2013.12.048. Epub 2013 Dec 18. Bioorg Med Chem Lett. 2014. PMID: 24388690 Free article.
Novel 3,4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90.
Baruchello R, Simoni D, Grisolia G, Barbato G, Marchetti P, Rondanin R, Mangiola S, Giannini G, Brunetti T, Alloatti D, Gallo G, Ciacci A, Vesci L, Castorina M, Milazzo FM, Cervoni ML, Guglielmi MB, Barbarino M, Foderà R, Pisano C, Cabri W. Baruchello R, et al. Among authors: barbarino m. J Med Chem. 2011 Dec 22;54(24):8592-604. doi: 10.1021/jm201155e. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22066525
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Zuco V, Zanchi C, Lanzi C, Beretta GL, Supino R, Pisano C, Barbarino M, Zanier R, Bucci F, Aulicino C, Carminati P, Zunino F. Zuco V, et al. Among authors: barbarino m. Neoplasia. 2005 Jul;7(7):667-77. doi: 10.1593/neo.05127. Neoplasia. 2005. PMID: 16026646 Free PMC article.
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