Sawyer DB - Search Results

1

Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity.

Sawyer DB, Zuppinger C, Miller TA, Eppenberger HM, Suter TM. Sawyer DB, et al. Circulation. 2002 Apr 2;105(13):1551-4. doi: 10.1161/01.cir.0000013839.41224.1c. Circulation. 2002. PMID: 11927521

2

Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt.

Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB. Fukazawa R, et al. Among authors: sawyer db. J Mol Cell Cardiol. 2003 Dec;35(12):1473-9. doi: 10.1016/j.yjmcc.2003.09.012. J Mol Cell Cardiol. 2003. PMID: 14654373

3

Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes.

Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, Suter TM, Liao R, Sawyer DB. Lim CC, et al. Among authors: sawyer db. J Biol Chem. 2004 Feb 27;279(9):8290-9. doi: 10.1074/jbc.M308033200. Epub 2003 Dec 14. J Biol Chem. 2004. PMID: 14676206 Free article.

4

Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro.

Cote GM, Miller TA, Lebrasseur NK, Kuramochi Y, Sawyer DB. Cote GM, et al. Among authors: sawyer db. Exp Cell Res. 2005 Nov 15;311(1):135-46. doi: 10.1016/j.yexcr.2005.08.017. Epub 2005 Sep 26. Exp Cell Res. 2005. PMID: 16185687

5

Palmitate alters neuregulin signaling and biology in cardiac myocytes.

Miller TA, Icli B, Cote GM, Lebrasseur NK, Borkan SC, Pimentel DR, Peng X, Sawyer DB. Miller TA, et al. Among authors: sawyer db. Biochem Biophys Res Commun. 2009 Jan 30;379(1):32-7. doi: 10.1016/j.bbrc.2008.11.150. Epub 2008 Dec 12. Biochem Biophys Res Commun. 2009. PMID: 19070592 Free PMC article.

6

Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes.

Pentassuglia L, Graf M, Lane H, Kuramochi Y, Cote G, Timolati F, Sawyer DB, Zuppinger C, Suter TM. Pentassuglia L, et al. Among authors: sawyer db. Exp Cell Res. 2009 Apr 15;315(7):1302-12. doi: 10.1016/j.yexcr.2009.02.001. Epub 2009 Feb 12. Exp Cell Res. 2009. PMID: 19331811 Free PMC article.

7

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.

Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB. Miller TA, et al. Among authors: sawyer db. Biochem Biophys Res Commun. 2005 Oct 14;336(1):309-15. doi: 10.1016/j.bbrc.2005.08.088. Biochem Biophys Res Commun. 2005. PMID: 16126172

8

Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle.

Lebrasseur NK, Coté GM, Miller TA, Fielding RA, Sawyer DB. Lebrasseur NK, et al. Among authors: sawyer db. Am J Physiol Cell Physiol. 2003 May;284(5):C1149-55. doi: 10.1152/ajpcell.00487.2002. Epub 2003 Jan 2. Am J Physiol Cell Physiol. 2003. PMID: 12519750 Free article.

9

Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes.

Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-Krasinski J, Baliga R, Wang J, Siwik DA, Singh K, Pagano P, Colucci WS, Sawyer DB. Pimentel DR, et al. Among authors: sawyer db. Circ Res. 2001 Aug 31;89(5):453-60. doi: 10.1161/hh1701.096615. Circ Res. 2001. PMID: 11532907

10

Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane.

Sawyer DB, Fukazawa R, Arstall MA, Kelly RA. Sawyer DB, et al. Circ Res. 1999 Feb 19;84(3):257-65. doi: 10.1161/01.res.84.3.257. Circ Res. 1999. PMID: 10024299

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