Senderowicz AM - Search Results

1

Flavopiridol, a novel cyclin-dependent kinase inhibitor, in clinical development.

Zhai S, Senderowicz AM, Sausville EA, Figg WD. Zhai S, et al. Among authors: senderowicz am. Ann Pharmacother. 2002 May;36(5):905-11. doi: 10.1345/aph.1A162. Ann Pharmacother. 2002. PMID: 11978170 Review.

2

Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms.

Tan AR, Headlee D, Messmann R, Sausville EA, Arbuck SG, Murgo AJ, Melillo G, Zhai S, Figg WD, Swain SM, Senderowicz AM. Tan AR, et al. Among authors: senderowicz am. J Clin Oncol. 2002 Oct 1;20(19):4074-82. doi: 10.1200/JCO.2002.01.043. J Clin Oncol. 2002. PMID: 12351605 Clinical Trial.

3

Clinical pharmacology and pharmacogenetics of flavopiridol 1-h i.v. infusion in patients with refractory neoplasms.

Zhai S, Sausville EA, Senderowicz AM, Ando Y, Headlee D, Messmann RA, Arbuck S, Murgo AJ, Melillo G, Fuse E, Figg WD. Zhai S, et al. Among authors: senderowicz am. Anticancer Drugs. 2003 Feb;14(2):125-35. doi: 10.1097/00001813-200302000-00006. Anticancer Drugs. 2003. PMID: 12569299 Clinical Trial.

4

Flavopiridol-related proinflammatory syndrome is associated with induction of interleukin-6.

Messmann RA, Ullmann CD, Lahusen T, Kalehua A, Wasfy J, Melillo G, Ding I, Headlee D, Figg WD, Sausville EA, Senderowicz AM. Messmann RA, et al. Among authors: senderowicz am. Clin Cancer Res. 2003 Feb;9(2):562-70. Clin Cancer Res. 2003. PMID: 12576419 Clinical Trial.

5

Clinical pharmacology of flavopiridol following a 72-hour continuous infusion.

Rudek MA, Bauer KS Jr, Lush RM 3rd, Stinson SF, Senderowicz AM, Headlee DJ, Arbuck SG, Cox MC, Murgo AJ, Sausville EA, Figg WD. Rudek MA, et al. Among authors: senderowicz am. Ann Pharmacother. 2003 Oct;37(10):1369-74. doi: 10.1345/aph.1C404. Ann Pharmacother. 2003. PMID: 14519054 Clinical Trial.

6

Cyclin-dependent kinases: initial approaches to exploit a novel therapeutic target.

Sausville EA, Zaharevitz D, Gussio R, Meijer L, Louarn-Leost M, Kunick C, Schultz R, Lahusen T, Headlee D, Stinson S, Arbuck SG, Senderowicz A. Sausville EA, et al. Pharmacol Ther. 1999 May-Jun;82(2-3):285-92. doi: 10.1016/s0163-7258(98)00062-x. Pharmacol Ther. 1999. PMID: 10454206 Review.

7

Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

Senderowicz AM, Headlee D, Stinson SF, Lush RM, Kalil N, Villalba L, Hill K, Steinberg SM, Figg WD, Tompkins A, Arbuck SG, Sausville EA. Senderowicz AM, et al. J Clin Oncol. 1998 Sep;16(9):2986-99. doi: 10.1200/JCO.1998.16.9.2986. J Clin Oncol. 1998. PMID: 9738567 Clinical Trial.

8

Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.

Patel V, Senderowicz AM, Pinto D Jr, Igishi T, Raffeld M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS. Patel V, et al. Among authors: senderowicz am. J Clin Invest. 1998 Nov 1;102(9):1674-81. doi: 10.1172/JCI3661. J Clin Invest. 1998. PMID: 9802881 Free PMC article.

9

Preclinical and clinical development of cyclin-dependent kinase modulators.

Senderowicz AM, Sausville EA. Senderowicz AM, et al. J Natl Cancer Inst. 2000 Mar 1;92(5):376-87. doi: 10.1093/jnci/92.5.376. J Natl Cancer Inst. 2000. PMID: 10699068 Review.

10

Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.

Patel V, Lahusen T, Sy T, Sausville EA, Gutkind JS, Senderowicz AM. Patel V, et al. Among authors: senderowicz am. Cancer Res. 2002 Mar 1;62(5):1401-9. Cancer Res. 2002. PMID: 11888912

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