Matter H - Search Results

1

Structural requirements for inhibition of the neuronal nitric oxide synthase (NOS-I): 3D-QSAR analysis of 4-oxo- and 4-amino-pteridine-based inhibitors.

Matter H, Kotsonis P, Klingler O, Strobel H, Fröhlich LG, Frey A, Pfleiderer W, Schmidt HH. Matter H, et al. J Med Chem. 2002 Jul 4;45(14):2923-41. doi: 10.1021/jm020074g. J Med Chem. 2002. PMID: 12086480

2

Selecting optimally diverse compounds from structure databases: a validation study of two-dimensional and three-dimensional molecular descriptors.

Matter H. Matter H. J Med Chem. 1997 Apr 11;40(8):1219-29. doi: 10.1021/jm960352+. J Med Chem. 1997. PMID: 9111296

3

Random or rational design? Evaluation of diverse compound subsets from chemical structure databases.

Pötter T, Matter H. Pötter T, et al. Among authors: matter h. J Med Chem. 1998 Feb 12;41(4):478-88. doi: 10.1021/jm9700878. J Med Chem. 1998. PMID: 9484498

4

Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis.

Matter H, Schwab W, Barbier D, Billen G, Haase B, Neises B, Schudok M, Thorwart W, Schreuder H, Brachvogel V, Lönze P, Weithmann KU. Matter H, et al. J Med Chem. 1999 Jun 3;42(11):1908-20. doi: 10.1021/jm980631s. J Med Chem. 1999. PMID: 10354399

5

Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: structure-activity relationship of antagonists of (6R)-5,6,7,8-tetrahydrobiopterin cofactor.

Fröhlich LG, Kotsonis P, Traub H, Taghavi-Moghadam S, Al-Masoudi N, Hofmann H, Strobel H, Matter H, Pfleiderer W, Schmidt HH. Fröhlich LG, et al. Among authors: matter h. J Med Chem. 1999 Oct 7;42(20):4108-21. doi: 10.1021/jm981129a. J Med Chem. 1999. PMID: 10514281

6

Affinity and selectivity of matrix metalloproteinase inhibitors: a chemometrical study from the perspective of ligands and proteins.

Matter H, Schwab W. Matter H, et al. J Med Chem. 1999 Nov 4;42(22):4506-23. doi: 10.1021/jm990250u. J Med Chem. 1999. PMID: 10579815

7

Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors.

Heinelt U, Herok S, Matter H, Wildgoose P. Heinelt U, et al. Among authors: matter h. Bioorg Med Chem Lett. 2001 Jan 22;11(2):227-30. doi: 10.1016/s0960-894x(00)00631-4. Bioorg Med Chem Lett. 2001. PMID: 11206465

8

Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin.

Kotsonis P, Fröhlich LG, Raman CS, Li H, Berg M, Gerwig R, Groehn V, Kang Y, Al-Masoudi N, Taghavi-Moghadam S, Mohr D, Münch U, Schnabel J, Martásek P, Masters BS, Strobel H, Poulos T, Matter H, Pfleiderer W, Schmidt HH. Kotsonis P, et al. Among authors: matter h. J Biol Chem. 2001 Dec 28;276(52):49133-41. doi: 10.1074/jbc.M011469200. Epub 2001 Oct 5. J Biol Chem. 2001. PMID: 11590164 Free article.

9

Structural classification of protein kinases using 3D molecular interaction field analysis of their ligand binding sites: target family landscapes.

Naumann T, Matter H. Naumann T, et al. Among authors: matter h. J Med Chem. 2002 Jun 6;45(12):2366-78. doi: 10.1021/jm011002c. J Med Chem. 2002. PMID: 12036347

10

Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.

Matter H, Defossa E, Heinelt U, Blohm PM, Schneider D, Müller A, Herok S, Schreuder H, Liesum A, Brachvogel V, Lönze P, Walser A, Al-Obeidi F, Wildgoose P. Matter H, et al. J Med Chem. 2002 Jun 20;45(13):2749-69. doi: 10.1021/jm0111346. J Med Chem. 2002. PMID: 12061878

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