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HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication.
Cicala C, Arthos J, Selig SM, Dennis G Jr, Hosack DA, Van Ryk D, Spangler ML, Steenbeke TD, Khazanie P, Gupta N, Yang J, Daucher M, Lempicki RA, Fauci AS. Cicala C, et al. Among authors: fauci as. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9380-5. doi: 10.1073/pnas.142287999. Epub 2002 Jun 27. Proc Natl Acad Sci U S A. 2002. PMID: 12089333 Free PMC article.
Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals.
Chun TW, Justement JS, Lempicki RA, Yang J, Dennis G Jr, Hallahan CW, Sanford C, Pandya P, Liu S, McLaughlin M, Ehler LA, Moir S, Fauci AS. Chun TW, et al. Among authors: fauci as. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1908-13. doi: 10.1073/pnas.0437640100. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. PMID: 12552096 Free PMC article.
HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.
Cicala C, Arthos J, Censoplano N, Cruz C, Chung E, Martinelli E, Lempicki RA, Natarajan V, VanRyk D, Daucher M, Fauci AS. Cicala C, et al. Among authors: fauci as. Virology. 2006 Feb 5;345(1):105-14. doi: 10.1016/j.virol.2005.09.052. Epub 2005 Nov 2. Virology. 2006. PMID: 16260021 Free article.
R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells.
Cicala C, Arthos J, Martinelli E, Censoplano N, Cruz CC, Chung E, Selig SM, Van Ryk D, Yang J, Jagannatha S, Chun TW, Ren P, Lempicki RA, Fauci AS. Cicala C, et al. Among authors: fauci as. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3746-51. doi: 10.1073/pnas.0511237103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505369 Free PMC article.
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS. Arthos J, et al. Among authors: fauci as. Nat Immunol. 2008 Mar;9(3):301-9. doi: 10.1038/ni1566. Epub 2008 Feb 10. Nat Immunol. 2008. PMID: 18264102
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J. Cicala C, et al. Among authors: fauci as. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20877-82. doi: 10.1073/pnas.0911796106. Epub 2009 Nov 20. Proc Natl Acad Sci U S A. 2009. PMID: 19933330 Free PMC article.
1,073 results