Burk O - Search Results

1

Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors.

Siegsmund M, Brinkmann U, Scháffeler E, Weirich G, Schwab M, Eichelbaum M, Fritz P, Burk O, Decker J, Alken P, Rothenpieler U, Kerb R, Hoffmeyer S, Brauch H. Siegsmund M, et al. Among authors: burk o. J Am Soc Nephrol. 2002 Jul;13(7):1847-54. doi: 10.1097/01.asn.0000019412.87412.bc. J Am Soc Nephrol. 2002. PMID: 12089380

2

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo.

Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmöller J, Johne A, Cascorbi I, Gerloff T, Roots I, Eichelbaum M, Brinkmann U. Hoffmeyer S, et al. Among authors: burk o. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3473-8. doi: 10.1073/pnas.97.7.3473. Proc Natl Acad Sci U S A. 2000. PMID: 10716719 Free PMC article.

3

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.

Geick A, Eichelbaum M, Burk O. Geick A, et al. Among authors: burk o. J Biol Chem. 2001 May 4;276(18):14581-7. doi: 10.1074/jbc.M010173200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297522 Free article.

4

The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin.

Burk O, Brenner SS, Hofmann U, Tegude H, Igel S, Schwab M, Eichelbaum M, Alscher MD. Burk O, et al. Clin Pharmacol Ther. 2010 Nov;88(5):685-94. doi: 10.1038/clpt.2010.176. Epub 2010 Sep 15. Clin Pharmacol Ther. 2010. PMID: 20844484

5

Sex is a major determinant of CYP3A4 expression in human liver.

Wolbold R, Klein K, Burk O, Nüssler AK, Neuhaus P, Eichelbaum M, Schwab M, Zanger UM. Wolbold R, et al. Among authors: burk o. Hepatology. 2003 Oct;38(4):978-88. doi: 10.1053/jhep.2003.50393. Hepatology. 2003. PMID: 14512885

6

A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression.

Burk O, Arnold KA, Geick A, Tegude H, Eichelbaum M. Burk O, et al. Biol Chem. 2005 Jun;386(6):503-13. doi: 10.1515/BC.2005.060. Biol Chem. 2005. PMID: 16006237

7

The effect of rifampin treatment on intestinal expression of human MRP transporters.

Fromm MF, Kauffmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, Eichelbaum M, Siegmund W, Schrenk D. Fromm MF, et al. Among authors: burk o. Am J Pathol. 2000 Nov;157(5):1575-80. doi: 10.1016/S0002-9440(10)64794-3. Am J Pathol. 2000. PMID: 11073816 Free PMC article.

8

Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.

von Richter O, Burk O, Fromm MF, Thon KP, Eichelbaum M, Kivistö KT. von Richter O, et al. Among authors: burk o. Clin Pharmacol Ther. 2004 Mar;75(3):172-83. doi: 10.1016/j.clpt.2003.10.008. Clin Pharmacol Ther. 2004. PMID: 15001968

9

Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver.

Lang T, Hitzl M, Burk O, Mornhinweg E, Keil A, Kerb R, Klein K, Zanger UM, Eichelbaum M, Fromm MF. Lang T, et al. Among authors: burk o. Pharmacogenetics. 2004 Mar;14(3):155-64. doi: 10.1097/00008571-200403000-00003. Pharmacogenetics. 2004. PMID: 15167703

10

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Nies AT, Koepsell H, Winter S, Burk O, Klein K, Kerb R, Zanger UM, Keppler D, Schwab M, Schaeffeler E. Nies AT, et al. Among authors: burk o. Hepatology. 2009 Oct;50(4):1227-40. doi: 10.1002/hep.23103. Hepatology. 2009. PMID: 19591196

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