Arnold E - Search Results

1

Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo.

Julias JG, McWilliams MJ, Sarafianos SG, Arnold E, Hughes SH. Julias JG, et al. Among authors: arnold e. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9515-20. doi: 10.1073/pnas.142123199. Epub 2002 Jul 1. Proc Natl Acad Sci U S A. 2002. PMID: 12093908 Free PMC article.

2

The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.

Boyer PL, Sarafianos SG, Arnold E, Hughes SH. Boyer PL, et al. Among authors: arnold e. J Virol. 2002 Apr;76(7):3248-56. doi: 10.1128/jvi.76.7.3248-3256.2002. J Virol. 2002. PMID: 11884549 Free PMC article.

3

Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.

Boyer PL, Sarafianos SG, Arnold E, Hughes SH. Boyer PL, et al. Among authors: arnold e. J Virol. 2002 Sep;76(18):9143-51. doi: 10.1128/jvi.76.18.9143-9151.2002. J Virol. 2002. PMID: 12186898 Free PMC article.

4

Mutation of amino acids in the connection domain of human immunodeficiency virus type 1 reverse transcriptase that contact the template-primer affects RNase H activity.

Julias JG, McWilliams MJ, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. Julias JG, et al. Among authors: arnold e. J Virol. 2003 Aug;77(15):8548-54. doi: 10.1128/jvi.77.15.8548-8554.2003. J Virol. 2003. PMID: 12857924 Free PMC article.

5

Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.

McWilliams MJ, Julias JG, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. McWilliams MJ, et al. Among authors: arnold e. J Virol. 2003 Oct;77(20):11150-7. doi: 10.1128/jvi.77.20.11150-11157.2003. J Virol. 2003. PMID: 14512562 Free PMC article.

6

Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.

Boyer PL, Imamichi T, Sarafianos SG, Arnold E, Hughes SH. Boyer PL, et al. Among authors: arnold e. J Virol. 2004 Sep;78(18):9987-97. doi: 10.1128/JVI.78.18.9987-9997.2004. J Virol. 2004. PMID: 15331732 Free PMC article.

7

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

Boyer PL, Tantillo C, Jacobo-Molina A, Nanni RG, Ding J, Arnold E, Hughes SH. Boyer PL, et al. Among authors: arnold e. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4882-6. doi: 10.1073/pnas.91.11.4882. Proc Natl Acad Sci U S A. 1994. PMID: 7515182 Free PMC article.

8

Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase.

Gao HQ, Boyer PL, Arnold E, Hughes SH. Gao HQ, et al. Among authors: arnold e. J Mol Biol. 1998 Apr 3;277(3):559-72. doi: 10.1006/jmbi.1998.1624. J Mol Biol. 1998. PMID: 9533880

9

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.

Sarafianos SG, Das K, Clark AD Jr, Ding J, Boyer PL, Hughes SH, Arnold E. Sarafianos SG, et al. Among authors: arnold e. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10027-32. doi: 10.1073/pnas.96.18.10027. Proc Natl Acad Sci U S A. 1999. PMID: 10468556 Free PMC article.

10

Gao HQ, Sarafianos SG, Arnold E, Hughes SH. Gao HQ, et al. Among authors: arnold e. J Mol Biol. 1999 Dec 17;294(5):1097-113. doi: 10.1006/jmbi.1999.3325. J Mol Biol. 1999. PMID: 10600369

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