Kelso A - Search Results

1

The fluorolysis assay, a highly sensitive method for measuring the cytolytic activity of T cells at very low numbers.

Kienzle N, Olver S, Buttigieg K, Kelso A. Kienzle N, et al. Among authors: kelso a. J Immunol Methods. 2002 Sep 15;267(2):99-108. doi: 10.1016/s0022-1759(02)00150-3. J Immunol Methods. 2002. PMID: 12165431

2

A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression.

Kienzle N, Buttigieg K, Groves P, Kawula T, Kelso A. Kienzle N, et al. Among authors: kelso a. J Immunol. 2002 Feb 15;168(4):1672-81. doi: 10.4049/jimmunol.168.4.1672. J Immunol. 2002. PMID: 11823496

3

Progressive differentiation and commitment of CD8+ T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4.

Kienzle N, Olver S, Buttigieg K, Groves P, Janas ML, Baz A, Kelso A. Kienzle N, et al. Among authors: kelso a. J Immunol. 2005 Feb 15;174(4):2021-9. doi: 10.4049/jimmunol.174.4.2021. J Immunol. 2005. PMID: 15699131

4

Tumor-derived interleukin-4 reduces tumor clearance and deviates the cytokine and granzyme profile of tumor-induced CD8+ T cells.

Olver S, Groves P, Buttigieg K, Morris ES, Janas ML, Kelso A, Kienzle N. Olver S, et al. Among authors: kelso a. Cancer Res. 2006 Jan 1;66(1):571-80. doi: 10.1158/0008-5472.CAN-05-1362. Cancer Res. 2006. PMID: 16397274 Free article.

5

Interleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo.

Olver S, Apte SH, Baz A, Kelso A, Kienzle N. Olver S, et al. Among authors: kelso a. Immunology. 2013 Jun;139(2):187-96. doi: 10.1111/imm.12068. Immunology. 2013. PMID: 23311920 Free PMC article.

6

The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation.

Kelso A, Costelloe EO, Johnson BJ, Groves P, Buttigieg K, Fitzpatrick DR. Kelso A, et al. Int Immunol. 2002 Jun;14(6):605-13. doi: 10.1093/intimm/dxf028. Int Immunol. 2002. PMID: 12039912

7

Profiling the CD8low phenotype, an alternative career choice for CD8 T cells during primary differentiation.

Kienzle N, Baz A, Kelso A. Kienzle N, et al. Among authors: kelso a. Immunol Cell Biol. 2004 Feb;82(1):75-83. doi: 10.1111/j.1440-1711.2004.01210.x. Immunol Cell Biol. 2004. PMID: 14984598 Review.

8

Memory cytolytic T-lymphocytes: induction, regulation and implications for vaccine design.

Baz A, Jackson DC, Kienzle N, Kelso A. Baz A, et al. Among authors: kelso a. Expert Rev Vaccines. 2005 Oct;4(5):711-23. doi: 10.1586/14760584.4.5.711. Expert Rev Vaccines. 2005. PMID: 16221072 Free article. Review.

9

IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation.

Janas ML, Groves P, Kienzle N, Kelso A. Janas ML, et al. Among authors: kelso a. J Immunol. 2005 Dec 15;175(12):8003-10. doi: 10.4049/jimmunol.175.12.8003. J Immunol. 2005. PMID: 16339537

10

Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses.

Baz A, Buttigieg K, Zeng W, Rizkalla M, Jackson DC, Groves P, Kelso A. Baz A, et al. Among authors: kelso a. Vaccine. 2008 May 19;26(21):2570-9. doi: 10.1016/j.vaccine.2008.03.022. Epub 2008 Mar 31. Vaccine. 2008. PMID: 18420312

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