Nicholas RA - Search Results

1

Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae.

Olesky M, Hobbs M, Nicholas RA. Olesky M, et al. Among authors: nicholas ra. Antimicrob Agents Chemother. 2002 Sep;46(9):2811-20. doi: 10.1128/AAC.46.9.2811-2820.2002. Antimicrob Agents Chemother. 2002. PMID: 12183233 Free PMC article.

2

Expression and purification of a soluble form of penicillin-binding protein 2 from both penicillin-susceptible and penicillin-resistant Neisseria gonorrhoeae.

Schultz DE, Spratt BG, Nicholas RA. Schultz DE, et al. Among authors: nicholas ra. Protein Expr Purif. 1991 Oct-Dec;2(5-6):339-49. doi: 10.1016/1046-5928(91)90092-w. Protein Expr Purif. 1991. PMID: 1821807

3

Cloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitidis.

Ropp PA, Nicholas RA. Ropp PA, et al. Among authors: nicholas ra. J Bacteriol. 1997 Apr;179(8):2783-7. doi: 10.1128/jb.179.8.2783-2787.1997. J Bacteriol. 1997. PMID: 9098083 Free PMC article.

4

Evidence that the p2y3 receptor is the avian homologue of the mammalian P2Y6 receptor.

Li Q, Olesky M, Palmer RK, Harden TK, Nicholas RA. Li Q, et al. Among authors: nicholas ra. Mol Pharmacol. 1998 Sep;54(3):541-6. doi: 10.1124/mol.54.3.541. Mol Pharmacol. 1998. PMID: 9730913

5

Nucleotide sequence of a three gene cluster in Neisseria Gonorrhoeae encoding ribosomal proteins S6, S18, and L9.

Ropp PA, Nicholas RA. Ropp PA, et al. Among authors: nicholas ra. DNA Seq. 1998;9(5-6):341-5. doi: 10.3109/10425179809008474. DNA Seq. 1998. PMID: 10524762

6

Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae.

Ropp PA, Hu M, Olesky M, Nicholas RA. Ropp PA, et al. Among authors: nicholas ra. Antimicrob Agents Chemother. 2002 Mar;46(3):769-77. doi: 10.1128/AAC.46.3.769-777.2002. Antimicrob Agents Chemother. 2002. PMID: 11850260 Free PMC article.

7

Neisseria gonorrhoeae penicillin-binding protein 3 exhibits exceptionally high carboxypeptidase and beta-lactam binding activities.

Stefanova ME, Tomberg J, Olesky M, Höltje JV, Gutheil WG, Nicholas RA. Stefanova ME, et al. Among authors: nicholas ra. Biochemistry. 2003 Dec 16;42(49):14614-25. doi: 10.1021/bi0350607. Biochemistry. 2003. PMID: 14661974

8

The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability.

Zhao S, Tobiason DM, Hu M, Seifert HS, Nicholas RA. Zhao S, et al. Among authors: nicholas ra. Mol Microbiol. 2005 Sep;57(5):1238-51. doi: 10.1111/j.1365-2958.2005.04752.x. Mol Microbiol. 2005. PMID: 16101998 Free PMC article.

9

High-level chromosomally mediated tetracycline resistance in Neisseria gonorrhoeae results from a point mutation in the rpsJ gene encoding ribosomal protein S10 in combination with the mtrR and penB resistance determinants.

Hu M, Nandi S, Davies C, Nicholas RA. Hu M, et al. Among authors: nicholas ra. Antimicrob Agents Chemother. 2005 Oct;49(10):4327-34. doi: 10.1128/AAC.49.10.4327-4334.2005. Antimicrob Agents Chemother. 2005. PMID: 16189114 Free PMC article.

10

Porin-mediated antibiotic resistance in Neisseria gonorrhoeae: ion, solute, and antibiotic permeation through PIB proteins with penB mutations.

Olesky M, Zhao S, Rosenberg RL, Nicholas RA. Olesky M, et al. Among authors: nicholas ra. J Bacteriol. 2006 Apr;188(7):2300-8. doi: 10.1128/JB.188.7.2300-2308.2006. J Bacteriol. 2006. PMID: 16547016 Free PMC article.

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