Osin P - Search Results

1

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.

Edwards SM, Kote-Jarai Z, Meitz J, Hamoudi R, Hope Q, Osin P, Jackson R, Southgate C, Singh R, Falconer A, Dearnaley DP, Ardern-Jones A, Murkin A, Dowe A, Kelly J, Williams S, Oram R, Stevens M, Teare DM, Ponder BA, Gayther SA, Easton DF, Eeles RA; Cancer Research UK/Bristish Prostate Group UK Familial Prostate Cancer Study Collaborators; British Association of Urological Surgeons Section of Oncology. Edwards SM, et al. Among authors: osin p. Am J Hum Genet. 2003 Jan;72(1):1-12. doi: 10.1086/345310. Epub 2002 Dec 9. Am J Hum Genet. 2003. PMID: 12474142 Free PMC article.

2

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.

Edwards SM, Evans DG, Hope Q, Norman AR, Barbachano Y, Bullock S, Kote-Jarai Z, Meitz J, Falconer A, Osin P, Fisher C, Guy M, Jhavar SG, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Forrest MS, Dearnaley DP, Ardern-Jones AT, Page EC, Easton DF, Eeles RA; UK Genetic Prostate Cancer Study Collaborators and BAUS Section of Oncology. Edwards SM, et al. Among authors: osin p. Br J Cancer. 2010 Sep 7;103(6):918-24. doi: 10.1038/sj.bjc.6605822. Epub 2010 Aug 24. Br J Cancer. 2010. PMID: 20736950 Free PMC article.

3

Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls.

Locke I, Kote-Jarai Z, Fackler MJ, Bancroft E, Osin P, Nerurkar A, Izatt L, Pichert G, Gui GP, Eeles RA. Locke I, et al. Among authors: osin p. Breast Cancer Res. 2007;9(1):R20. doi: 10.1186/bcr1657. Breast Cancer Res. 2007. PMID: 17324252 Free PMC article.

4

Loss of heterozygosity at the BRCA1 and BRCA2 loci detected in ductal lavage fluid from BRCA gene mutation carriers and controls.

Locke I, Kote-Jarai Z, Bancroft E, Bullock S, Jugurnauth S, Osin P, Nerurkar A, Izatt L, Pichert G, Gui GP, Eeles RA. Locke I, et al. Among authors: osin p. Cancer Epidemiol Biomarkers Prev. 2006 Jul;15(7):1399-402. doi: 10.1158/1055-9965.EPI-05-0971. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 16835343

5

BCL10 is rarely mutated in human prostate carcinoma, small-cell lung cancer, head and neck tumours, renal carcinoma and sarcomas. MPT Collaborators, St George's Hospital Collaborators.

Gill S, Broni J, Jefferies S, Osin P, Kovacs G, Maitland NJ, Eeles R, Edwards SM, Dyer MJ, Willis TG, Cooper CS. Gill S, et al. Among authors: osin p. Br J Cancer. 1999 Jul;80(10):1565-8. doi: 10.1038/sj.bjc.6690561. Br J Cancer. 1999. PMID: 10408398 Free PMC article.

6

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

Lakhani SR, Van De Vijver MJ, Jacquemier J, Anderson TJ, Osin PP, McGuffog L, Easton DF. Lakhani SR, et al. Among authors: osin pp. J Clin Oncol. 2002 May 1;20(9):2310-8. doi: 10.1200/JCO.2002.09.023. J Clin Oncol. 2002. PMID: 11981002

7

Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers.

Osin P, Gusterson BA, Philp E, Waller J, Bartek J, Peto J, Crook T. Osin P, et al. Eur J Cancer. 1998 Oct;34(11):1683-6. doi: 10.1016/s0959-8049(98)00248-2. Eur J Cancer. 1998. PMID: 9893652

8

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours.

Crook T, Brooks LA, Crossland S, Osin P, Barker KT, Waller J, Philp E, Smith PD, Yulug I, Peto J, Parker G, Allday MJ, Crompton MR, Gusterson BA. Crook T, et al. Among authors: osin p. Oncogene. 1998 Oct 1;17(13):1681-9. doi: 10.1038/sj.onc.1202106. Oncogene. 1998. PMID: 9796697

9

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions.

Smith PD, Crossland S, Parker G, Osin P, Brooks L, Waller J, Philp E, Crompton MR, Gusterson BA, Allday MJ, Crook T. Smith PD, et al. Among authors: osin p. Oncogene. 1999 Apr 15;18(15):2451-9. doi: 10.1038/sj.onc.1202565. Oncogene. 1999. PMID: 10229196

10

Concomitant inactivation of p53 and Chk2 in breast cancer.

Sullivan A, Yuille M, Repellin C, Reddy A, Reelfs O, Bell A, Dunne B, Gusterson BA, Osin P, Farrell PJ, Yulug I, Evans A, Ozcelik T, Gasco M, Crook T. Sullivan A, et al. Among authors: osin p. Oncogene. 2002 Feb 21;21(9):1316-24. doi: 10.1038/sj.onc.1205207. Oncogene. 2002. PMID: 11857075

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