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Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
Edwards SM, Kote-Jarai Z, Meitz J, Hamoudi R, Hope Q, Osin P, Jackson R, Southgate C, Singh R, Falconer A, Dearnaley DP, Ardern-Jones A, Murkin A, Dowe A, Kelly J, Williams S, Oram R, Stevens M, Teare DM, Ponder BA, Gayther SA, Easton DF, Eeles RA; Cancer Research UK/Bristish Prostate Group UK Familial Prostate Cancer Study Collaborators; British Association of Urological Surgeons Section of Oncology. Edwards SM, et al. Among authors: southgate c. Am J Hum Genet. 2003 Jan;72(1):1-12. doi: 10.1086/345310. Epub 2002 Dec 9. Am J Hum Genet. 2003. PMID: 12474142 Free PMC article.
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer.
Bevan S, Edwards SM, Ardern Jones A, Dowe A, Southgate C, Dearnaley D, Easton DF, Houlston RS, Eeles RA; CRC/BPG UK Familial Prostate Cancer Study Collaborators. Bevan S, et al. Among authors: southgate c. Prostate Cancer Prostatic Dis. 2003;6(1):12-4. doi: 10.1038/sj.pcan.4500616. Prostate Cancer Prostatic Dis. 2003. PMID: 12664059
ATM polymorphisms as risk factors for prostate cancer development.
Angèle S, Falconer A, Edwards SM, Dörk T, Bremer M, Moullan N, Chapot B, Muir K, Houlston R, Norman AR, Bullock S, Hope Q, Meitz J, Dearnaley D, Dowe A, Southgate C, Ardern-Jones A, Easton DF, Eeles RA, Hall J. Angèle S, et al. Among authors: southgate c. Br J Cancer. 2004 Aug 16;91(4):783-7. doi: 10.1038/sj.bjc.6602007. Br J Cancer. 2004. PMID: 15280931 Free PMC article.
Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.
Hope Q, Bullock S, Evans C, Meitz J, Hamel N, Edwards SM, Severi G, Dearnaley D, Jhavar S, Southgate C, Falconer A, Dowe A, Muir K, Houlston RS, Engert JC, Roquis D, Sinnett D, Simard J, Heimdal K, Møller P, Maehle L, Badzioch M, Eeles RA, Easton DF, English DR, Southey MC, Hopper JL, Foulkes WD, Giles GG; Cancer Research UK/British Association of Urological Surgeons' Section of Oncology Collaborators. Hope Q, et al. Among authors: southgate c. Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):397-402. doi: 10.1158/1055-9965.EPI-04-0202. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15734964 Free article.
39 results