Crooke ST - Search Results

1

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis.

Vickers TA, Koo S, Bennett CF, Crooke ST, Dean NM, Baker BF. Vickers TA, et al. Among authors: crooke st. J Biol Chem. 2003 Feb 28;278(9):7108-18. doi: 10.1074/jbc.M210326200. Epub 2002 Dec 23. J Biol Chem. 2003. PMID: 12500975 Free article.

2

Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice.

Liang XH, Vickers TA, Guo S, Crooke ST. Liang XH, et al. Among authors: crooke st. Nucleic Acids Res. 2011 Feb;39(3):e13. doi: 10.1093/nar/gkq1121. Epub 2010 Nov 9. Nucleic Acids Res. 2011. PMID: 21062825 Free PMC article.

3

Defining the factors that contribute to on-target specificity of antisense oligonucleotides.

Lima WF, Vickers TA, Nichols J, Li C, Crooke ST. Lima WF, et al. Among authors: crooke st. PLoS One. 2014 Jul 29;9(7):e101752. doi: 10.1371/journal.pone.0101752. eCollection 2014. PLoS One. 2014. PMID: 25072142 Free PMC article.

4

Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.

Vickers TA, Crooke ST. Vickers TA, et al. Among authors: crooke st. PLoS One. 2014 Oct 9;9(10):e108625. doi: 10.1371/journal.pone.0108625. eCollection 2014. PLoS One. 2014. PMID: 25299183 Free PMC article.

5

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA.

Vickers TA, Crooke ST. Vickers TA, et al. Among authors: crooke st. Nucleic Acids Res. 2015 Oct 15;43(18):8955-63. doi: 10.1093/nar/gkv920. Epub 2015 Sep 17. Nucleic Acids Res. 2015. PMID: 26384424 Free PMC article.

6

Antisense technology: A review.

Crooke ST, Liang XH, Baker BF, Crooke RM. Crooke ST, et al. Among authors: crooke rm. J Biol Chem. 2021 Jan-Jun;296:100416. doi: 10.1016/j.jbc.2021.100416. Epub 2021 Feb 16. J Biol Chem. 2021. PMID: 33600796 Free PMC article. Review.

7

Progress in antisense oligonucleotide therapeutics.

Crooke ST, Bennett CF. Crooke ST, et al. Annu Rev Pharmacol Toxicol. 1996;36:107-29. doi: 10.1146/annurev.pa.36.040196.000543. Annu Rev Pharmacol Toxicol. 1996. PMID: 8725384 Review.

8

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.

Wu H, Lima WF, Zhang H, Fan A, Sun H, Crooke ST. Wu H, et al. Among authors: crooke st. J Biol Chem. 2004 Apr 23;279(17):17181-9. doi: 10.1074/jbc.M311683200. Epub 2004 Feb 11. J Biol Chem. 2004. PMID: 14960586 Free article.

9

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells.

Vickers TA, Lima WF, Nichols JG, Crooke ST. Vickers TA, et al. Among authors: crooke st. Nucleic Acids Res. 2007;35(19):6598-610. doi: 10.1093/nar/gkm663. Epub 2007 Sep 28. Nucleic Acids Res. 2007. PMID: 17905815 Free PMC article.

10

Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 'Slicer' independent and can be mediated by Ago1.

Vickers TA, Lima WF, Wu H, Nichols JG, Linsley PS, Crooke ST. Vickers TA, et al. Among authors: crooke st. Nucleic Acids Res. 2009 Nov;37(20):6927-41. doi: 10.1093/nar/gkp735. Epub 2009 Sep 18. Nucleic Acids Res. 2009. PMID: 19767612 Free PMC article.

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