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A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor.
Jungbluth AA, Stockert E, Huang HJ, Collins VP, Coplan K, Iversen K, Kolb D, Johns TJ, Scott AM, Gullick WJ, Ritter G, Cohen L, Scanlan MJ, Cavenee WK, Old LJ. Jungbluth AA, et al. Among authors: stockert e. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):639-44. doi: 10.1073/pnas.232686499. Epub 2003 Jan 6. Proc Natl Acad Sci U S A. 2003. PMID: 12515857 Free PMC article.
Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.
Johns TG, Stockert E, Ritter G, Jungbluth AA, Huang HJ, Cavenee WK, Smyth FE, Hall CM, Watson N, Nice EC, Gullick WJ, Old LJ, Burgess AW, Scott AM. Johns TG, et al. Among authors: stockert e. Int J Cancer. 2002 Mar 20;98(3):398-408. doi: 10.1002/ijc.10189. Int J Cancer. 2002. PMID: 11920591
Immunomic analysis of human sarcoma.
Lee SY, Obata Y, Yoshida M, Stockert E, Williamson B, Jungbluth AA, Chen YT, Old LJ, Scanlan MJ. Lee SY, et al. Among authors: stockert e. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2651-6. doi: 10.1073/pnas.0437972100. Epub 2003 Feb 24. Proc Natl Acad Sci U S A. 2003. PMID: 12601173 Free PMC article.
Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.
Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. Johns TG, et al. Among authors: stockert e. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15871-6. doi: 10.1073/pnas.2036503100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676326 Free PMC article.
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.
Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. Perera RM, et al. Among authors: stockert e. Clin Cancer Res. 2005 Sep 1;11(17):6390-9. doi: 10.1158/1078-0432.CCR-04-2653. Clin Cancer Res. 2005. PMID: 16144944
Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.
Mishima K, Johns TG, Luwor RB, Scott AM, Stockert E, Jungbluth AA, Ji XD, Suvarna P, Voland JR, Old LJ, Huang HJ, Cavenee WK. Mishima K, et al. Among authors: stockert e. Cancer Res. 2001 Jul 15;61(14):5349-54. Cancer Res. 2001. PMID: 11454673
143 results