Kieran M - Search Results

1

Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria.

Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Sugimoto H, et al. Among authors: kieran m. J Biol Chem. 2003 Apr 11;278(15):12605-8. doi: 10.1074/jbc.C300012200. Epub 2003 Jan 21. J Biol Chem. 2003. PMID: 12538598 Free article.

2

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression.

Hamano Y, Sugimoto H, Soubasakos MA, Kieran M, Olsen BR, Lawler J, Sudhakar A, Kalluri R. Hamano Y, et al. Among authors: kieran m. Cancer Res. 2004 Mar 1;64(5):1570-4. doi: 10.1158/0008-5472.can-03-3126. Cancer Res. 2004. PMID: 14996710

3

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors.

Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, Yerramalla U, Benjamin LE, Lawler J, Kieran M, Shah A, Kalluri R. Sund M, et al. Among authors: kieran m. Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2934-9. doi: 10.1073/pnas.0500180102. Epub 2005 Feb 14. Proc Natl Acad Sci U S A. 2005. PMID: 15710885 Free PMC article.

4

Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth.

Mundel TM, Yliniemi AM, Maeshima Y, Sugimoto H, Kieran M, Kalluri R. Mundel TM, et al. Among authors: kieran m. Int J Cancer. 2008 Apr 15;122(8):1738-44. doi: 10.1002/ijc.23269. Int J Cancer. 2008. PMID: 18074349

5

The VEGF pathway in cancer and disease: responses, resistance, and the path forward.

Kieran MW, Kalluri R, Cho YJ. Kieran MW, et al. Cold Spring Harb Perspect Med. 2012 Dec 1;2(12):a006593. doi: 10.1101/cshperspect.a006593. Cold Spring Harb Perspect Med. 2012. PMID: 23209176 Free PMC article. Review.

6

Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity.

Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Eikesdal HP, et al. Among authors: kieran m. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15040-5. doi: 10.1073/pnas.0807055105. Epub 2008 Sep 25. Proc Natl Acad Sci U S A. 2008. PMID: 18818312 Free PMC article.

7

Identification of fibroblast heterogeneity in the tumor microenvironment.

Sugimoto H, Mundel TM, Kieran MW, Kalluri R. Sugimoto H, et al. Among authors: kieran mw. Cancer Biol Ther. 2006 Dec;5(12):1640-6. doi: 10.4161/cbt.5.12.3354. Epub 2006 Dec 5. Cancer Biol Ther. 2006. PMID: 17106243 Free article.

8

Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.

Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Xie L, et al. Exp Biol Med (Maywood). 2008 Feb;233(2):155-62. doi: 10.3181/0706-RM-167. Exp Biol Med (Maywood). 2008. PMID: 18222970

9

Contribution of bone microenvironment to leukemogenesis and leukemia progression.

Ayala F, Dewar R, Kieran M, Kalluri R. Ayala F, et al. Among authors: kieran m. Leukemia. 2009 Dec;23(12):2233-41. doi: 10.1038/leu.2009.175. Epub 2009 Sep 3. Leukemia. 2009. PMID: 19727127 Free PMC article. Review.

10

Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors.

Kieran MW, Supko JG, Wallace D, Fruscio R, Poussaint TY, Phillips P, Pollack I, Packer R, Boyett JM, Blaney S, Banerjee A, Geyer R, Friedman H, Goldman S, Kun LE, Macdonald T; Pediatric Brain Tumor Consortium. Kieran MW, et al. Pediatr Blood Cancer. 2009 Feb;52(2):169-76. doi: 10.1002/pbc.21873. Pediatr Blood Cancer. 2009. PMID: 19065567 Free PMC article. Clinical Trial.

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