Schulze-Osthoff K - Search Results

1

Many cuts to ruin: a comprehensive update of caspase substrates.

Fischer U, Jänicke RU, Schulze-Osthoff K. Fischer U, et al. Cell Death Differ. 2003 Jan;10(1):76-100. doi: 10.1038/sj.cdd.4401160. Cell Death Differ. 2003. PMID: 12655297 Free PMC article. Review.

2

Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner.

Engels IH, Totzke G, Fischer U, Schulze-Osthoff K, Jänicke RU. Engels IH, et al. Mol Cell Biol. 2005 Apr;25(7):2808-18. doi: 10.1128/MCB.25.7.2808-2818.2005. Mol Cell Biol. 2005. PMID: 15767684 Free PMC article.

3

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment.

Janssen K, Pohlmann S, Jänicke RU, Schulze-Osthoff K, Fischer U. Janssen K, et al. Blood. 2007 Nov 15;110(10):3662-72. doi: 10.1182/blood-2007-02-073213. Epub 2007 Jul 25. Blood. 2007. PMID: 17652622 Free article.

4

Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis.

Sohn D, Schulze-Osthoff K, Jänicke RU. Sohn D, et al. J Biol Chem. 2005 Feb 18;280(7):5267-73. doi: 10.1074/jbc.M408585200. Epub 2004 Dec 15. J Biol Chem. 2005. PMID: 15611097 Free article.

5

Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation.

Essmann F, Bantel H, Totzke G, Engels IH, Sinha B, Schulze-Osthoff K, Jänicke RU. Essmann F, et al. Cell Death Differ. 2003 Nov;10(11):1260-72. doi: 10.1038/sj.cdd.4401301. Cell Death Differ. 2003. PMID: 12894214

6

Apoptosis-based therapies and drug targets.

Fischer U, Schulze-Osthoff K. Fischer U, et al. Cell Death Differ. 2005 Aug;12 Suppl 1:942-61. doi: 10.1038/sj.cdd.4401556. Cell Death Differ. 2005. PMID: 15665817 Review.

7

Unique and overlapping substrate specificities of caspase-8 and caspase-10.

Fischer U, Stroh C, Schulze-Osthoff K. Fischer U, et al. Oncogene. 2006 Jan 5;25(1):152-9. doi: 10.1038/sj.onc.1209015. Oncogene. 2006. PMID: 16186808

8

The dark side of a tumor suppressor: anti-apoptotic p53.

Jänicke RU, Sohn D, Schulze-Osthoff K. Jänicke RU, et al. Cell Death Differ. 2008 Jun;15(6):959-76. doi: 10.1038/cdd.2008.33. Epub 2008 Mar 21. Cell Death Differ. 2008. PMID: 18356920 Review.

9

Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.

Sohn D, Graupner V, Neise D, Essmann F, Schulze-Osthoff K, Jänicke RU. Sohn D, et al. Cell Death Differ. 2009 Jun;16(6):869-78. doi: 10.1038/cdd.2009.17. Epub 2009 Feb 20. Cell Death Differ. 2009. PMID: 19229248

10

Does caspase inhibition promote clonogenic tumor growth?

Fischer U, Janssen K, Schulze-Osthoff K. Fischer U, et al. Cell Cycle. 2007 Dec 15;6(24):3048-53. doi: 10.4161/cc.6.24.5118. Epub 2007 Oct 2. Cell Cycle. 2007. PMID: 18073530 Review.

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