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Page 1
How do Parkin mutations result in neurodegeneration?
Imai Y, Takahashi R. Imai Y, et al. Among authors: takahashi r. Curr Opin Neurobiol. 2004 Jun;14(3):384-9. doi: 10.1016/j.conb.2004.04.002. Curr Opin Neurobiol. 2004. PMID: 15194120 Review.
Parkin and endoplasmic reticulum stress.
Takahashi R, Imai Y, Hattori N, Mizuno Y. Takahashi R, et al. Ann N Y Acad Sci. 2003 Jun;991:101-6. doi: 10.1111/j.1749-6632.2003.tb07467.x. Ann N Y Acad Sci. 2003. PMID: 12846978 Review.
Pael-R is accumulated in Lewy bodies of Parkinson's disease.
Murakami T, Shoji M, Imai Y, Inoue H, Kawarabayashi T, Matsubara E, Harigaya Y, Sasaki A, Takahashi R, Abe K. Murakami T, et al. Among authors: takahashi r. Ann Neurol. 2004 Mar;55(3):439-42. doi: 10.1002/ana.20064. Ann Neurol. 2004. PMID: 14991825
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation.
Kitao Y, Imai Y, Ozawa K, Kataoka A, Ikeda T, Soda M, Nakimawa K, Kiyama H, Stern DM, Hori O, Wakamatsu K, Ito S, Itohara S, Takahashi R, Ogawa S. Kitao Y, et al. Among authors: takahashi r. Hum Mol Genet. 2007 Jan 1;16(1):50-60. doi: 10.1093/hmg/ddl439. Epub 2006 Nov 20. Hum Mol Genet. 2007. PMID: 17116640
3,084 results