Tsuda Y - Search Results

1

Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond.

Okada Y, Fujita Y, Motoyama T, Tsuda Y, Yokoi T, Li T, Sasaki Y, Ambo A, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: tsuda y. Bioorg Med Chem. 2003 May 1;11(9):1983-94. doi: 10.1016/s0968-0896(03)00068-3. Bioorg Med Chem. 2003. PMID: 12670649

2

A selective plasmin inhibitor, trans-aminomethylcyclohexanecarbonyl-L-(O-picolyl)tyrosine-octylamide (YO-2), induces thymocyte apoptosis.

Lee E, Enomoto R, Takemura K, Tsuda Y, Okada Y. Lee E, et al. Among authors: tsuda y. Biochem Pharmacol. 2002 Apr 1;63(7):1315-23. doi: 10.1016/s0006-2952(02)00866-3. Biochem Pharmacol. 2002. PMID: 11960608

3

Endomorphins and related opioid peptides.

Okada Y, Tsuda Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: tsuda y. Vitam Horm. 2002;65:257-79. doi: 10.1016/s0083-6729(02)65067-8. Vitam Horm. 2002. PMID: 12481550 Review.

4

Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia.

Okada Y, Tsuda Y, Fujita Y, Yokoi T, Sasaki Y, Ambo A, Konishi R, Nagata M, Salvadori S, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: tsuda y. J Med Chem. 2003 Jul 17;46(15):3201-9. doi: 10.1021/jm020459z. J Med Chem. 2003. PMID: 12852751

5

Novel 2',6'-dimethyl-L-tyrosine-containing pyrazinone opioid mimetic mu-agonists with potent antinociceptive activity in mice.

Jinsmaa Y, Okada Y, Tsuda Y, Shiotani K, Sasaki Y, Ambo A, Bryant SD, Lazarus LH. Jinsmaa Y, et al. Among authors: tsuda y. J Pharmacol Exp Ther. 2004 Apr;309(1):432-8. doi: 10.1124/jpet.103.060061. Epub 2004 Jan 12. J Pharmacol Exp Ther. 2004. PMID: 14718580

6

Oral bioavailability of a new class of micro-opioid receptor agonists containing 3,6-bis[Dmt-NH(CH(2))(n)]-2(1H)-pyrazinone with central-mediated analgesia.

Jinsmaa Y, Miyazaki A, Fujita Y, Li T, Fujisawa Y, Shiotani K, Tsuda Y, Yokoi T, Ambo A, Sasaki Y, Bryant SD, Lazarus LH, Okada Y. Jinsmaa Y, et al. Among authors: tsuda y. J Med Chem. 2004 May 6;47(10):2599-610. doi: 10.1021/jm0304616. J Med Chem. 2004. PMID: 15115401

7

Application of liquid chromatography-tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally.

Igarashi K, Murabayashi Y, Hotta K, Kitamura Y, Kasuya F, Shiotani K, Tingyou L, Miyazaki A, Tsuda Y, Okada Y, Fukushima S. Igarashi K, et al. Among authors: tsuda y. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jun 25;806(1):53-7. doi: 10.1016/j.jchromb.2004.02.024. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15149611

8

Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.

Fujita Y, Tsuda Y, Li T, Motoyama T, Takahashi M, Shimizu Y, Yokoi T, Sasaki Y, Ambo A, Kita A, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Fujita Y, et al. Among authors: tsuda y. J Med Chem. 2004 Jul 1;47(14):3591-9. doi: 10.1021/jm030649p. J Med Chem. 2004. PMID: 15214786

9

The structure-activity relationship of various YO compounds, novel plasmin inhibitors, in the apoptosis induction.

Enomoto R, Sugahara C, Komai T, Suzuki C, Kinoshita N, Hosoda A, Yoshikawa A, Tsuda Y, Okada Y, Lee E. Enomoto R, et al. Among authors: tsuda y. Biochim Biophys Acta. 2004 Nov 1;1674(3):291-8. doi: 10.1016/j.bbagen.2004.07.004. Biochim Biophys Acta. 2004. PMID: 15541298

10

Development of potent mu-opioid receptor ligands using unique tyrosine analogues of endomorphin-2.

Li T, Fujita Y, Tsuda Y, Miyazaki A, Ambo A, Sasaki Y, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Li T, et al. Among authors: tsuda y. J Med Chem. 2005 Jan 27;48(2):586-92. doi: 10.1021/jm049384k. J Med Chem. 2005. PMID: 15658871

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