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The G972R variant of the insulin receptor substrate-1 (IRS-1) gene is associated with insulin resistance in "uncomplicated" obese subjects evaluated by hyperinsulinemic-euglycemic clamp.
Baroni MG, Leonetti F, Sentinelli F, Romeo S, Filippi E, Fanelli M, Ribaudo MC, Zappaterreno A, Fallarino M, Di Mario U. Baroni MG, et al. Among authors: zappaterreno a. J Endocrinol Invest. 2004 Sep;27(8):754-9. doi: 10.1007/BF03347518. J Endocrinol Invest. 2004. PMID: 15636429
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