Bhagat L - Search Results

1

Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Kandimalla ER, Bhagat L, Wang D, Yu D, Zhu FG, Tang J, Wang H, Huang P, Zhang R, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Nucleic Acids Res. 2003 May 1;31(9):2393-400. doi: 10.1093/nar/gkg343. Nucleic Acids Res. 2003. PMID: 12711684 Free PMC article.

2

Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.

Kandimalla ER, Bhagat L, Wang D, Yu D, Sullivan T, La Monica N, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Nucleic Acids Res. 2013 Apr 1;41(6):3947-61. doi: 10.1093/nar/gkt078. Epub 2013 Feb 8. Nucleic Acids Res. 2013. PMID: 23396449 Free PMC article.

3

Potent CpG oligonucleotides containing phosphodiester linkages: in vitro and in vivo immunostimulatory properties.

Yu D, Zhu FG, Bhagat L, Wang H, Kandimalla ER, Zhang R, Agrawal S. Yu D, et al. Among authors: bhagat l. Biochem Biophys Res Commun. 2002 Sep 13;297(1):83-90. doi: 10.1016/s0006-291x(02)02127-7. Biochem Biophys Res Commun. 2002. PMID: 12220512

4

Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity.

Kandimalla ER, Bhagat L, Yu D, Cong Y, Tang J, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Bioconjug Chem. 2002 Sep-Oct;13(5):966-74. doi: 10.1021/bc0200374. Bioconjug Chem. 2002. PMID: 12236778

5

'Immunomers'--novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents.

Yu D, Kandimalla ER, Bhagat L, Tang JY, Cong Y, Tang J, Agrawal S. Yu D, et al. Among authors: bhagat l. Nucleic Acids Res. 2002 Oct 15;30(20):4460-9. doi: 10.1093/nar/gkf582. Nucleic Acids Res. 2002. PMID: 12384593 Free PMC article.

6

Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNA.

Yu D, Kandimalla ER, Zhao Q, Bhagat L, Cong Y, Agrawal S. Yu D, et al. Among authors: bhagat l. Bioorg Med Chem. 2003 Feb 6;11(3):459-64. doi: 10.1016/s0968-0896(02)00430-3. Bioorg Med Chem. 2003. PMID: 12517441

7

CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents.

Bhagat L, Zhu FG, Yu D, Tang J, Wang H, Kandimalla ER, Zhang R, Agrawal S. Bhagat L, et al. Biochem Biophys Res Commun. 2003 Jan 24;300(4):853-61. doi: 10.1016/s0006-291x(02)02943-1. Biochem Biophys Res Commun. 2003. PMID: 12559951

8

Secondary structures in CpG oligonucleotides affect immunostimulatory activity.

Kandimalla ER, Bhagat L, Cong YP, Pandey RK, Yu D, Zhao Q, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Biochem Biophys Res Commun. 2003 Jul 11;306(4):948-53. doi: 10.1016/s0006-291x(03)01080-5. Biochem Biophys Res Commun. 2003. PMID: 12821134

9

A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif.

Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14303-8. doi: 10.1073/pnas.2335947100. Epub 2003 Nov 10. Proc Natl Acad Sci U S A. 2003. PMID: 14610275 Free PMC article.

10

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S. Kandimalla ER, et al. Among authors: bhagat l. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6925-30. doi: 10.1073/pnas.0501729102. Epub 2005 Apr 28. Proc Natl Acad Sci U S A. 2005. PMID: 15860583 Free PMC article.

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