Heine A - Search Results

1

Structural basis for antibody catalysis of a cationic cyclization reaction.

Zhu X, Heine A, Monnat F, Houk KN, Janda KD, Wilson IA. Zhu X, et al. Among authors: heine a. J Mol Biol. 2003 May 23;329(1):69-83. doi: 10.1016/s0022-2836(03)00406-6. J Mol Biol. 2003. PMID: 12742019

2

A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.

Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. Rader C, et al. Among authors: heine a. J Mol Biol. 2003 Sep 26;332(4):889-99. doi: 10.1016/s0022-2836(03)00992-6. J Mol Biol. 2003. PMID: 12972259

3

Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution.

Heine A, Luz JG, Wong CH, Wilson IA. Heine A, et al. J Mol Biol. 2004 Oct 29;343(4):1019-34. doi: 10.1016/j.jmb.2004.08.066. J Mol Biol. 2004. PMID: 15476818

4

The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.

Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF 3rd, Wilson IA. Zhu X, et al. Among authors: heine a. J Mol Biol. 2004 Nov 5;343(5):1269-80. doi: 10.1016/j.jmb.2004.08.102. J Mol Biol. 2004. PMID: 15491612

5

Structural origins of efficient proton abstraction from carbon by a catalytic antibody.

Debler EW, Ito S, Seebeck FP, Heine A, Hilvert D, Wilson IA. Debler EW, et al. Among authors: heine a. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):4984-9. doi: 10.1073/pnas.0409207102. Epub 2005 Mar 23. Proc Natl Acad Sci U S A. 2005. PMID: 15788533 Free PMC article.

6

An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.

Heine A, Stura EA, Yli-Kauhaluoma JT, Gao C, Deng Q, Beno BR, Houk KN, Janda KD, Wilson IA. Heine A, et al. Science. 1998 Mar 20;279(5358):1934-40. doi: 10.1126/science.279.5358.1934. Science. 1998. PMID: 9506943

7

Crystal structure of a cocaine-binding antibody.

Larsen NA, Zhou B, Heine A, Wirsching P, Janda KD, Wilson IA. Larsen NA, et al. Among authors: heine a. J Mol Biol. 2001 Aug 3;311(1):9-15. doi: 10.1006/jmbi.2001.4839. J Mol Biol. 2001. PMID: 11469854

8

Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.

Larsen NA, Heine A, Crane L, Cravatt BF, Lerner RA, Wilson IA. Larsen NA, et al. Among authors: heine a. J Mol Biol. 2001 Nov 16;314(1):93-102. doi: 10.1006/jmbi.2001.5112. J Mol Biol. 2001. PMID: 11724535

9

Structure determination of a cocaine hydrolytic antibody from a pseudomerohedrally twinned crystal.

Larsen NA, Heine A, de Prada P, Redwan el-R, Yeates TO, Landry DW, Wilson IA. Larsen NA, et al. Among authors: heine a. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2055-9. doi: 10.1107/s0907444902017420. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454464

10

Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.

DeSantis G, Liu J, Clark DP, Heine A, Wilson IA, Wong CH. DeSantis G, et al. Among authors: heine a. Bioorg Med Chem. 2003 Jan 2;11(1):43-52. doi: 10.1016/s0968-0896(02)00429-7. Bioorg Med Chem. 2003. PMID: 12467706

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