Houk KN - Search Results

1

Structural basis for antibody catalysis of a cationic cyclization reaction.

Zhu X, Heine A, Monnat F, Houk KN, Janda KD, Wilson IA. Zhu X, et al. Among authors: houk kn. J Mol Biol. 2003 May 23;329(1):69-83. doi: 10.1016/s0022-2836(03)00406-6. J Mol Biol. 2003. PMID: 12742019

2

Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis.

Gouverneur VE, Houk KN, de Pascual-Teresa B, Beno B, Janda KD, Lerner RA. Gouverneur VE, et al. Among authors: houk kn. Science. 1993 Oct 8;262(5131):204-8. doi: 10.1126/science.8211138. Science. 1993. PMID: 8211138

3

An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.

Heine A, Stura EA, Yli-Kauhaluoma JT, Gao C, Deng Q, Beno BR, Houk KN, Janda KD, Wilson IA. Heine A, et al. Among authors: houk kn. Science. 1998 Mar 20;279(5358):1934-40. doi: 10.1126/science.279.5358.1934. Science. 1998. PMID: 9506943

4

Structural basis for antibody catalysis of a disfavored ring closure reaction.

Gruber K, Zhou B, Houk KN, Lerner RA, Shevlin CG, Wilson IA. Gruber K, et al. Among authors: houk kn. Biochemistry. 1999 Jun 1;38(22):7062-74. doi: 10.1021/bi990210s. Biochemistry. 1999. PMID: 10353817

5

Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.

Xu J, Deng Q, Chen J, Houk KN, Bartek J, Hilvert D, Wilson IA. Xu J, et al. Among authors: houk kn. Science. 1999 Dec 17;286(5448):2345-8. doi: 10.1126/science.286.5448.2345. Science. 1999. PMID: 10600746

6

Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.

Hotta K, Lange H, Tantillo DJ, Houk KN, Hilvert D, Wilson IA. Hotta K, et al. Among authors: houk kn. J Mol Biol. 2000 Oct 6;302(5):1213-25. doi: 10.1006/jmbi.2000.4503. J Mol Biol. 2000. PMID: 11183784

7

Shape complementarity, binding-site dynamics, and transition state stabilization: a theoretical study of Diels-Alder catalysis by antibody 1E9.

Chen J, Deng Q, Wang R, Houk K, Hilvert D. Chen J, et al. Chembiochem. 2000 Nov 17;1(4):255-61. doi: 10.1002/1439-7633(20001117)1:4<255::AID-CBIC255>3.0.CO;2-S. Chembiochem. 2000. PMID: 11828417

8

Experimental determination of the absolute enantioselectivity of an antibody-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity.

Cannizzaro CE, Ashley JA, Janda KD, Houk KN. Cannizzaro CE, et al. Among authors: houk kn. J Am Chem Soc. 2003 Mar 5;125(9):2489-506. doi: 10.1021/ja020879d. J Am Chem Soc. 2003. PMID: 12603137

9

Canonical binding arrays as molecular recognition elements in the immune system: tetrahedral anions and the ester hydrolysis transition state.

Tantillo DJ, Houk KN. Tantillo DJ, et al. Among authors: houk kn. Chem Biol. 2001 Jun;8(6):535-45. doi: 10.1016/s1074-5521(01)00035-7. Chem Biol. 2001. PMID: 11410373 Review.

10

Origins and predictions of stereoselective antibody catalysis: theoretical analysis of Diels-Alder catalysis by 39A11 and its germ-line antibody.

Zhang X, Deng Q, Yoo SH, Houk KN. Zhang X, et al. Among authors: houk kn. J Org Chem. 2002 Dec 13;67(25):9043-53. doi: 10.1021/jo0203894. J Org Chem. 2002. PMID: 12467427

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