Qiu S - Search Results

1

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.

Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, Ogura Y, Kawasaki A, Fukase K, Kusumoto S, Valvano MA, Foster SJ, Mak TW, Nuñez G, Inohara N. Chamaillard M, et al. Among authors: qiu s. Nat Immunol. 2003 Jul;4(7):702-7. doi: 10.1038/ni945. Epub 2003 Jun 6. Nat Immunol. 2003. PMID: 12796777

2

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition.

Tanabe T, Chamaillard M, Ogura Y, Zhu L, Qiu S, Masumoto J, Ghosh P, Moran A, Predergast MM, Tromp G, Williams CJ, Inohara N, Núñez G. Tanabe T, et al. Among authors: qiu s. EMBO J. 2004 Apr 7;23(7):1587-97. doi: 10.1038/sj.emboj.7600175. Epub 2004 Mar 25. EMBO J. 2004. PMID: 15044951 Free PMC article.

3

Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.

Masumoto J, Yang K, Varambally S, Hasegawa M, Tomlins SA, Qiu S, Fujimoto Y, Kawasaki A, Foster SJ, Horie Y, Mak TW, Núñez G, Chinnaiyan AM, Fukase K, Inohara N. Masumoto J, et al. Among authors: qiu s. J Exp Med. 2006 Jan 23;203(1):203-13. doi: 10.1084/jem.20051229. Epub 2006 Jan 17. J Exp Med. 2006. PMID: 16418393 Free PMC article.

4

Structure-based design, synthesis, evaluation, and crystallographic studies of conformationally constrained Smac mimetics as inhibitors of the X-linked inhibitor of apoptosis protein (XIAP).

Sun H, Stuckey JA, Nikolovska-Coleska Z, Qin D, Meagher JL, Qiu S, Lu J, Yang CY, Saito NG, Wang S. Sun H, et al. Among authors: qiu s. J Med Chem. 2008 Nov 27;51(22):7169-80. doi: 10.1021/jm8006849. J Med Chem. 2008. PMID: 18954041 Free PMC article.

5

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer.

Shangary S, Ding K, Qiu S, Nikolovska-Coleska Z, Bauer JA, Liu M, Wang G, Lu Y, McEachern D, Bernard D, Bradford CR, Carey TE, Wang S. Shangary S, et al. Among authors: qiu s. Mol Cancer Ther. 2008 Jun;7(6):1533-42. doi: 10.1158/1535-7163.MCT-08-0140. Mol Cancer Ther. 2008. PMID: 18566224 Free PMC article.

6

Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.

Sun H, Nikolovska-Coleska Z, Lu J, Meagher JL, Yang CY, Qiu S, Tomita Y, Ueda Y, Jiang S, Krajewski K, Roller PP, Stuckey JA, Wang S. Sun H, et al. Among authors: qiu s. J Am Chem Soc. 2007 Dec 12;129(49):15279-94. doi: 10.1021/ja074725f. Epub 2007 Nov 14. J Am Chem Soc. 2007. PMID: 17999504 Free PMC article.

7

Design of small-molecule peptidic and nonpeptidic Smac mimetics.

Sun H, Nikolovska-Coleska Z, Yang CY, Qian D, Lu J, Qiu S, Bai L, Peng Y, Cai Q, Wang S. Sun H, et al. Among authors: qiu s. Acc Chem Res. 2008 Oct;41(10):1264-77. doi: 10.1021/ar8000553. Acc Chem Res. 2008. PMID: 18937395 Free PMC article.

8

Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases.

Peng Y, Sun H, Nikolovska-Coleska Z, Qiu S, Yang CY, Lu J, Cai Q, Yi H, Kang S, Yang D, Wang S. Peng Y, et al. Among authors: qiu s. J Med Chem. 2008 Dec 25;51(24):8158-62. doi: 10.1021/jm801254r. J Med Chem. 2008. PMID: 19049347 Free PMC article.

9

Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity.

Sun H, Liu L, Lu J, Bai L, Li X, Nikolovska-Coleska Z, McEachern D, Yang CY, Qiu S, Yi H, Sun D, Wang S. Sun H, et al. Among authors: qiu s. J Med Chem. 2011 May 12;54(9):3306-18. doi: 10.1021/jm101651b. Epub 2011 Apr 13. J Med Chem. 2011. PMID: 21462933 Free PMC article.

10

SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP.

Lu J, Bai L, Sun H, Nikolovska-Coleska Z, McEachern D, Qiu S, Miller RS, Yi H, Shangary S, Sun Y, Meagher JL, Stuckey JA, Wang S. Lu J, et al. Among authors: qiu s. Cancer Res. 2008 Nov 15;68(22):9384-93. doi: 10.1158/0008-5472.CAN-08-2655. Cancer Res. 2008. PMID: 19010913 Free PMC article.

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