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Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance.
Ferlini C, Raspaglio G, Mozzetti S, Distefano M, Filippetti F, Martinelli E, Ferrandina G, Gallo D, Ranelletti FO, Scambia G. Ferlini C, et al. Mol Pharmacol. 2003 Jul;64(1):51-8. doi: 10.1124/mol.64.1.51. Mol Pharmacol. 2003. PMID: 12815160
From plasma membrane to cytoskeleton: a novel function for semaphorin 6A.
Prislei S, Mozzetti S, Filippetti F, De Donato M, Raspaglio G, Cicchillitti L, Scambia G, Ferlini C. Prislei S, et al. Among authors: ferlini c. Mol Cancer Ther. 2008 Jan;7(1):233-41. doi: 10.1158/1535-7163.MCT-07-0390. Epub 2008 Jan 9. Mol Cancer Ther. 2008. PMID: 18187809
Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77.
Ferlini C, Cicchillitti L, Raspaglio G, Bartollino S, Cimitan S, Bertucci C, Mozzetti S, Gallo D, Persico M, Fattorusso C, Campiani G, Scambia G. Ferlini C, et al. Cancer Res. 2009 Sep 1;69(17):6906-14. doi: 10.1158/0008-5472.CAN-09-0540. Epub 2009 Aug 11. Cancer Res. 2009. PMID: 19671798
Thiocolchicine dimers: a novel class of topoisomerase-I inhibitors.
Raspaglio G, Ferlini C, Mozzetti S, Prislei S, Gallo D, Das N, Scambia G. Raspaglio G, et al. Among authors: ferlini c. Biochem Pharmacol. 2005 Jan 1;69(1):113-21. doi: 10.1016/j.bcp.2004.09.004. Biochem Pharmacol. 2005. PMID: 15588720
118 results