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The kringle stabilizes urokinase binding to the urokinase receptor.
Bdeir K, Kuo A, Sachais BS, Rux AH, Bdeir Y, Mazar A, Higazi AA, Cines DB. Bdeir K, et al. Among authors: mazar a. Blood. 2003 Nov 15;102(10):3600-8. doi: 10.1182/blood-2003-03-0949. Epub 2003 Jul 24. Blood. 2003. PMID: 12881310 Free article.
Soluble human urokinase receptor is composed of two active units.
Higazi AA, Mazar A, Wang J, Quan N, Griffin R, Reilly R, Henkin J, Cines DB. Higazi AA, et al. Among authors: mazar a. J Biol Chem. 1997 Feb 21;272(8):5348-53. doi: 10.1074/jbc.272.8.5348. J Biol Chem. 1997. PMID: 9030610 Free article.
186 results